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2-Methoxy-7H-Pyrrolo[2,3-D]Pyrimidin-4-Amine CAS NO 100383-13-9


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CAS No.:100383-13-9

Grade:Pharmacy Grade

Content:99.9%

Brand:Customizable

Packaging:Customizable

Description

2-Methoxy-7H-Pyrrolo[2,3-D]Pyrimidin-4-Amine is a high-purity, advanced pharmaceutical intermediate belonging to the pyrrolopyrimidine class of heterocyclic compounds. This compound matters as a critical building block in the synthesis of novel, targeted therapeutic agents, particularly kinase inhibitors used in oncology research. Pharmaceutical R&D teams and fine chemical manufacturers need this high-value intermediate to develop next-generation drug candidates with improved efficacy and selectivity.

Application

  • Pharmaceutical Intermediate: Serves as a key scaffold in the synthesis of protein kinase inhibitors for cancer therapy.
  • Oncology Drug Discovery: Used in research and development of small molecule therapeutics targeting specific signaling pathways.
  • Biochemical Research: Employed as a reference standard or probe in enzymatic studies and mechanism-of-action research.
  • Preclinical Development: Utilized for producing batches of active pharmaceutical ingredients (APIs) for toxicology and formulation studies.
  • Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for cGMP-scale synthesis.
  • Academic Research: Used in university and institutional labs for medicinal chemistry and chemical biology projects.

Basic Information

Product Name 2-Methoxy-7H-Pyrrolo[2,3-D]Pyrimidin-4-Amine
CAS No. 100383-13-9
Molecular Formula C7H8N4O
Molecular Weight 164.16 g/mol
Synonyms 4-Amino-2-methoxy-7H-pyrrolo[2,3-d]pyrimidine; 2-Methoxy-7H-pyrrolo[2,3-d]pyrimidin-4-amine; 2-Methoxypyrrolo[2,3-d]pyrimidin-4-amine; 7H-Pyrrolo[2,3-d]pyrimidin-4-amine, 2-methoxy-; 100383-13-9; 2-Methoxy-7H-pyrrolo[2,3-d]pyrimidin-4-ylamine
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Quality Control

Our 2-Methoxy-7H-Pyrrolo[2,3-D]Pyrimidin-4-Amine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via NMR and mass spectrometry, to ensure it meets the high standards required for pharmaceutical R&D. Certificates of Analysis (COA) with full traceability are provided for every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption. For long-term storage, consider using desiccants.

Specification

Item Specification
Appearance White to off-white powder
Identification (IR) Conforms to structure
Identification (HPLC) Conforms to reference
Purity (HPLC) ≥98.0%
Water Content (KF) ≤1.0%
Residue on Ignition ≤0.1%
Heavy Metals ≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.

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