Description

5-Amino-2-Fluorophenol is a versatile fluorinated aromatic amine derivative, serving as a critical building block in advanced organic synthesis. Its molecular structure, featuring both an amino and a hydroxyl group on a fluorinated benzene ring, makes it a valuable intermediate for creating complex molecules with tailored properties. This compound is essential for research and production in the pharmaceutical, agrochemical, and specialty chemical industries, where it is used to develop active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for drugs targeting the central nervous system and oncology.
• Agrochemical Synthesis: Used in the development of novel herbicides, pesticides, and fungicides, leveraging the fluorine atom for enhanced bioactivity and stability.
• Dye and Pigment Manufacturing: Serves as a building block for producing advanced fluorinated dyes and organic pigments with improved lightfastness and color properties.
• Liquid Crystal & OLED Materials: A crucial intermediate in the synthesis of fluorinated compounds for electronic display technologies and organic light-emitting diodes.
• Polymer Modification: Incorporated into polymer chains to impart specific characteristics such as solubility, thermal stability, or chemical resistance.
• Chemical Research & Development: A valuable reagent in academic and industrial R&D for exploring new synthetic pathways and creating novel fluorinated compounds.

Basic Information

Product Name	5-Amino-2-Fluorophenol
CAS No.	100367-48-4
Molecular Formula	C6H6FNO
Molecular Weight	127.12 g/mol
Synonyms	2-Fluoro-5-aminophenol; 5-Amino-2-fluorophenol; 2-Fluoro-5-hydroxyaniline; 3-Fluoro-6-aminophenol; 5-Amino-2-fluoro-1-hydroxybenzene; 2-Fluoro-5-aminophenol; 1-Hydroxy-2-fluoro-5-aminobenzene; 5-Amino-2-fluorophenol (primary name)
EINECS	Contact for details

Quality Control

Our 5-Amino-2-Fluorophenol is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistency. We provide comprehensive Certificates of Analysis (COA) with every shipment, detailing all specification parameters. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring reliability for your critical synthesis processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture. Keep away from incompatible materials such as strong oxidizing agents.

Specification

Item	Specification
Appearance	Off-white to light brown crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	125 - 130 °C
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 20 ppm
Related Substances (HPLC)	Total impurities ≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.