Description

Leucinostatin D is a potent, non-ribosomal peptide antibiotic belonging to the leucinostatin family, identified by CAS No. 100334-47-2. This compound is valued for its significant biological activity, particularly as a strong antifungal and antitumor agent, making it a critical tool in biochemical and pharmacological research. It is primarily sought by researchers in pharmaceutical development, biotechnology, and academic institutions for investigating novel therapeutic pathways and antimicrobial mechanisms.

Application

• Antifungal Research: Used as a reference standard and active agent in studies targeting pathogenic fungi, including Candida and Aspergillus species.
• Antitumor and Cytotoxicity Studies: Employed in in vitro and in vivo research to investigate its inhibitory effects on various cancer cell lines.
• Biochemical Mechanism Research: Serves as a probe to study membrane disruption, ion channel activity, and mitochondrial function in eukaryotic cells.
• Pharmaceutical Development: Acts as a lead compound or intermediate in the discovery and synthesis of new antimicrobial and anticancer agents.
• Microbiology & Antibiotic Resistance Studies: Utilized to understand modes of action and to combat drug-resistant fungal infections.
• Reference Standard for Analysis: Provides a high-purity benchmark for quality control, method development, and identification in analytical laboratories (HPLC, LC-MS).

Basic Information

Product Name	Leucinostatin D
CAS No.	100334-47-2
Molecular Formula	C₆₃H₁₁₃N₁₃O₁₃
Molecular Weight	1284.6 g/mol
Synonyms	Leucinostatin D; Antibiotic A-21978D; Leucinostatin D (Antibiotic A 21978D); A-21978D; Leucinostatine D; UNII-6T9K9Q8F8W; 6T9K9Q8F8W; (2S)-2-[[(2S)-2-[[(2S,3S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-Amino-4-methylpentanoyl]amino]-4-methylpentanoyl]amino]-3-methylpentanoyl]amino]-4-methylpentanoyl]amino]-3-hydroxy-4-methylpentanoyl]amino]-4-methylpentanoyl]amino]-3-methylpentanoyl]amino]-4-methylpentanoyl]amino]-3-hydroxy-4-methylpentanoyl]amino]-4-methylpentanoyl]amino]-3-methylpentanoyl]amino]-4-methylpentanoic acid
EINECS	Contact for details

Quality Control

Our Leucinostatin D is produced and handled under strict quality management protocols to ensure batch-to-batch consistency and high purity for research applications. Each lot undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via mass spectrometry. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting key specifications and test results.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dedicated freezer. Due to its hygroscopic (moisture-sensitive) nature, the container should be allowed to equilibrate to room temperature before opening to prevent condensation. For long-term storage, consider under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Identification (MS)	Conforms to reference standard
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 5.0%
Residue on Ignition	≤ 1.0%
Biological Activity	Assayed; COA provided

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.