Description

Ethyl 2-(Methylsulfanyl)-4-Morpholino-5-Pyrimidinecarboxylate is a high-purity pyrimidine derivative, a crucial advanced intermediate in modern pharmaceutical synthesis. This compound matters for its role as a key building block in the development of active pharmaceutical ingredients (APIs), particularly in kinase inhibitor research. Pharmaceutical R&D and fine chemical manufacturers need it to ensure reliable and scalable production of complex drug candidates. Its defined structure enables precise molecular construction for targeted therapeutic applications.

Application

• Pharmaceutical Intermediate: A critical building block for the synthesis of kinase inhibitors and other small-molecule APIs.
• Chemical Research & Development: Used in medicinal chemistry for lead optimization and structure-activity relationship (SAR) studies.
• Process Chemistry: Serves as a key starting material or intermediate in scalable GMP and non-GMP manufacturing processes.
• Contract Manufacturing (CDMO): Supplied to contract development and manufacturing organizations for custom synthesis projects.
• Academic Research: Utilized in university and institutional labs for exploratory organic synthesis and heterocyclic chemistry.

Basic Information

Product Name	Ethyl 2-(Methylsulfanyl)-4-Morpholino-5-Pyrimidinecarboxylate
CAS No.	100318-76-1
Molecular Formula	C12H17N3O3S
Molecular Weight	283.35 g/mol
Synonyms	Ethyl 2-(methylthio)-4-morpholinopyrimidine-5-carboxylate; 5-Pyrimidinecarboxylic acid, 2-(methylthio)-4-morpholino-, ethyl ester; 2-Methylsulfanyl-4-morpholin-4-yl-pyrimidine-5-carboxylic acid ethyl ester; 4-Morpholino-2-(methylthio)-5-pyrimidinecarboxylic acid ethyl ester; Ethyl 4-morpholino-2-(methylthio)pyrimidine-5-carboxylate
EINECS	Contact for details

Quality Control

Our Ethyl 2-(Methylsulfanyl)-4-Morpholino-5-Pyrimidinecarboxylate is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for pharmaceutical R&D and manufacturing. A comprehensive Certificate of Analysis (COA) detailing purity, impurities, and physical characteristics is provided with every shipment. We support compliance with ICH guidelines for impurities in drug substances.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, containers should be kept in the original packaging or opaque containers until use.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.