Description

Tyrosyl-Arginyl-Phenylalanyl-Glycinamide is a synthetic tetrapeptide amide with the sequence Tyr-Arg-Phe-Gly-NH₂. This compound is of significant interest in biochemical and pharmaceutical research due to its role as a potential peptide intermediate or a model substrate for studying enzyme activity and receptor interactions. It is primarily utilized by research institutions, pharmaceutical developers, and biotechnology companies engaged in peptide synthesis, drug discovery, and metabolic pathway analysis.

Application

• Pharmaceutical Research & Development: Serves as a key intermediate in the synthesis of more complex bioactive peptides or peptidomimetics.
• Biochemical Assay Development: Used as a standard or substrate in enzymatic studies, particularly for proteases and kinases.
• Drug Discovery Screening: Employed in high-throughput screening (HTS) assays to identify novel therapeutic agents that interact with specific peptide sequences.
• Academic Research: Utilized in universities and research labs for studying peptide structure-activity relationships (SAR) and signal transduction pathways.
• Reference Standard: Acts as a certified reference material (CRM) for quality control and analytical method validation in peptide analysis.

Basic Information

Product Name	Tyrosyl-Arginyl-Phenylalanyl-Glycinamide
CAS No.	100304-60-7
Molecular Formula	C₃₁H₄₅N₁₁O₇
Molecular Weight	675.76 g/mol
Synonyms	Tyr-Arg-Phe-Gly-NH₂; YRFG-NH₂; H-Tyr-Arg-Phe-Gly-NH₂; Tetrapeptide amide YRFG; L-Tyrosyl-L-arginyl-L-phenylalylglycinamide; TRFG; 100304-60-7; UNII-9Q4J6F8F4M
EINECS	Contact for details

Quality Control

Our Tyrosyl-Arginyl-Phenylalanyl-Glycinamide is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, MS for identity confirmation, and chiral analysis to ensure stereochemical integrity. Certificates of Analysis (COA) detailing all specifications are provided to guarantee compliance with research-grade standards and traceability.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry environment. This product is hygroscopic (moisture-sensitive). Allow the vial to reach room temperature in a desiccator before opening to minimize moisture absorption.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC/MS)	Conforms
Purity (HPLC)	≥ 95.0%
Assay (Peptide Content)	≥ 80.0%
Single Impurity (HPLC)	≤ 2.0%
Water Content (KF)	≤ 5.0%
Optical Rotation	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.