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Angiotensin Ii (2-7) CAS NO 100291-80-3


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CAS No.:100291-80-3

Grade:Pharmacy Grade

Content:99.9%

Brand:Customizable

Packaging:Customizable

Description

Angiotensin II (2-7) is a bioactive peptide fragment derived from the renin-angiotensin system. This compound is a critical research tool for investigating cardiovascular physiology, neurobiology, and metabolic pathways. It is primarily utilized by pharmaceutical R&D teams, academic researchers, and diagnostic developers focusing on hypertension, heart failure, and related receptor studies.

Application

  • Biomedical Research: A key reagent for studying the structure-activity relationships of angiotensin peptides and their receptor subtypes (AT1, AT2).
  • Drug Discovery: Used as a reference standard and intermediate in the development of novel cardiovascular and neurological therapeutics.
  • Enzyme Activity Studies: Employed as a substrate to investigate the activity and inhibition of angiotensin-converting enzyme (ACE) and other proteases.
  • Diagnostic Development: Serves as an antigen or calibrator in the development of immunoassays for measuring angiotensin pathway components.
  • Cell Signaling & Physiology: Applied in in vitro and ex vivo models to explore cellular signaling cascades related to blood pressure regulation and fluid balance.

Basic Information

Product Name Angiotensin II (2-7)
CAS No. 100291-80-3
Molecular Formula C34H50N10O8
Molecular Weight 726.83 g/mol
Synonyms Angiotensin II Fragment 2-7; [Des-Asp1, Ile8]-Angiotensin II; Angiotensin (2-7); Ile8-Angiotensin II (2-7); DRVYIHP; H-Asp-Arg-Val-Tyr-Ile-His-Pro-OH; Ang-(2-7)
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Quality Control

Our Angiotensin II (2-7) is manufactured under strict quality management systems. Each batch is characterized and tested to ensure high purity and consistency, with comprehensive analysis including HPLC for purity and MS for identity confirmation. Certificates of Analysis (COA) detailing all specifications are provided with every shipment to support your research and regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry environment. This product is hygroscopic (moisture-sensitive). Allow the vial to equilibrate to room temperature in a desiccator before opening to minimize moisture uptake.

Specification

Item Specification
Appearance White to off-white powder
Identification (HPLC & MS) Conforms to reference standard
Purity (HPLC) ≥ 95.0%
Water Content (KF) ≤ 5.0%
Peptide Content ≥ 80.0%
Single Impurity (HPLC) ≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.

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