Description

7-(2-Cyanoethyl)Guanine is a specialized nucleobase derivative, a key intermediate in the synthesis of modified nucleosides and oligonucleotides. Its primary value lies in enabling precise chemical modifications for advanced research and development in life sciences. This high-purity compound is essential for pharmaceutical researchers, diagnostic developers, and biotechnology companies working on novel therapeutics, molecular probes, and antisense technologies.

Application

• Pharmaceutical Intermediate: Critical building block for the synthesis of novel antiviral and anticancer nucleoside analogs.
• Oligonucleotide Synthesis: Used in the preparation of modified DNA/RNA strands for research, diagnostics, and therapeutic applications.
• Bioconjugation & Probe Development: Serves as a precursor for creating labeled nucleotides used in fluorescence in situ hybridization (FISH) and other detection assays.
• Antisense & siRNA Research: Enables the incorporation of specific modifications to enhance the stability and efficacy of oligonucleotide-based therapeutics.
• Chemical Biology Tool: Utilized in studying enzyme mechanisms and nucleic acid interactions within academic and industrial R&D settings.
• Reference Standard: Serves as a high-purity analytical standard for quality control in nucleotide manufacturing and related research.

Basic Information

Product Name	7-(2-Cyanoethyl)Guanine
CAS No.	100234-52-4
Molecular Formula	C8H8N6O
Molecular Weight	204.19 g/mol
Synonyms	2-Amino-7-(2-cyanoethyl)-1,7-dihydro-6H-purin-6-one; 7-(2-Cyanoethyl)guanine; N7-(2-Cyanoethyl)guanine; Guanine, 7-(2-cyanoethyl)-; 1,7-Dihydro-2-amino-7-(2-cyanoethyl)-6H-purin-6-one; 7-Cyanoethylguanine; N7-(2-Cyanoethyl)guanine
EINECS	Contact for details

Quality Control

Our 7-(2-Cyanoethyl)Guanine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and stringent controls for residual solvents and moisture. We provide full traceability and Certificates of Analysis (COA) are available for every shipment to ensure compliance with your research and development specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to minimize exposure to atmospheric moisture. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.