Description

Pyroglutamyl-Seryl-Phenylalanine Amide is a high-purity synthetic tripeptide derivative, recognized for its role as a key intermediate in advanced pharmaceutical and cosmetic research. Its value lies in providing a reliable and consistent building block for the synthesis of complex bioactive molecules and peptide-based active ingredients. This compound is essential for R&D and production teams in the pharmaceutical, biotechnology, and high-end cosmetic industries, where precise molecular structure and purity are critical for efficacy and safety.

Application

• Pharmaceutical Intermediate: Serves as a crucial precursor in the synthesis of novel peptide-based drugs and therapeutic agents.
• Cosmetic Actives Development: Used in R&D for creating advanced anti-aging, skin-repair, and moisturizing peptide ingredients.
• Biochemical Research: A valuable tool in proteomics, enzymology, and cell signaling studies as a substrate or inhibitor analog.
• Peptide Library Synthesis: Employed in combinatorial chemistry for generating diverse peptide libraries for screening and discovery.
• Reference Standard: Acts as a certified reference material (CRM) for analytical method development and quality control in peptide manufacturing.

Basic Information

Product Name	Pyroglutamyl-Seryl-Phenylalanine Amide
CAS No.	100218-02-8
Molecular Formula	C₁₉H₂₆N₄O₆
Molecular Weight	406.44 g/mol
Synonyms	pGlu-Ser-Phe-NH₂; Pyroglutamylserylphenylalanine amide; 5-Oxo-L-prolyl-L-seryl-L-phenylalaninamide; L-Pyroglutamyl-L-seryl-L-phenylalaninamide; Pyr-Ser-Phe-NH2; (S)-2-((S)-2-((S)-5-Oxopyrrolidine-2-carboxamido)-3-hydroxypropanamido)-3-phenylpropanamide
EINECS	Contact for details

Quality Control

Our Pyroglutamyl-Seryl-Phenylalanine Amide is manufactured under strict quality management systems. Each batch is subjected to comprehensive analytical testing, including HPLC for purity, chiral analysis, and identity confirmation via mass spectrometry and NMR, to ensure it meets the stringent requirements for research and pharmaceutical-grade intermediates. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting compliance with agreed specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation. For long-term storage, consider desiccated conditions.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Assay	97.0% - 102.0% (on anhydrous basis)
Water Content (KF)	≤ 2.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.