Description

Gly-Gly-Ala-Ome.Hcl is a protected tripeptide derivative, specifically the methyl ester hydrochloride salt of the Glycyl-Glycyl-Alanine sequence. This compound serves as a crucial building block in solid-phase peptide synthesis (SPPS), enabling the controlled elongation of peptide chains. It is primarily utilized by research institutions and pharmaceutical companies engaged in the development of novel therapeutic peptides, diagnostic agents, and biochemical tools.

Application

• Solid-Phase Peptide Synthesis (SPPS): As a key intermediate for the controlled, stepwise assembly of longer, complex peptide sequences.
• Pharmaceutical Research & Development: For the synthesis of peptide-based drug candidates, prodrugs, and active pharmaceutical ingredients (APIs).
• Biochemical Research: Used in the study of enzyme-substrate interactions, protease specificity, and peptide hormone analogs.
• Combinatorial Chemistry Libraries: As a versatile monomer for generating diverse peptide libraries for high-throughput screening.
• Diagnostic Reagent Development: In the creation of labeled peptides for assays and imaging probes.
• Academic & Industrial Laboratories: For teaching advanced synthesis techniques and conducting fundamental peptide chemistry.

Basic Information

Product Name	Gly-Gly-Ala-Ome.Hcl
CAS No.	100047-94-7
Molecular Formula	C10H19N3O4 • HCl
Molecular Weight	281.74 g/mol
Synonyms	Glycyl-glycyl-L-alanine methyl ester hydrochloride; L-Alanine, glycylglycyl-, methyl ester, hydrochloride; H-Gly-Gly-Ala-OMe • HCl; Methyl N-[(2S)-2-[(2-aminoacetyl)amino]propanoyl]glycinate hydrochloride; Gly-Gly-L-Ala-OMe • HCl; Tripeptide derivative GGA-OMe HCl; N-Glycylglycyl-L-alanine methyl ester hydrochloride
EINECS	Contact for details

Quality Control

Our Gly-Gly-Ala-Ome.Hcl is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, chiral analysis, and identity confirmation. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment to ensure traceability and compliance with your research or production requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 15-25°C. This material is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation. For long-term storage, consider desiccated conditions.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Optical Rotation	Specific range provided on COA
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.