Description

7-(Chloromethyl)-3-Methyl-5H-[1,3]Thiazolo[3,2-A]Pyrimidin-5-One is a high-value heterocyclic organic compound featuring a fused thiazolopyrimidinone core, serving as a critical advanced intermediate in modern synthetic chemistry. Its molecular architecture, combining a reactive chloromethyl group with a complex bicyclic system, makes it indispensable for constructing sophisticated pharmacophores and functional materials. This compound is primarily sought after by research institutions and manufacturers in the pharmaceutical and agrochemical sectors for developing novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: A key building block for the synthesis of novel drug candidates, particularly in medicinal chemistry programs targeting central nervous system (CNS) disorders and infectious diseases.
• Agrochemical Synthesis: Used in the research and development of next-generation herbicides, fungicides, and insecticides, leveraging its heterocyclic structure for bioactivity.
• Organic Light-Emitting Diode (OLED) Materials: Serves as a precursor for electron-transport or host materials in OLED devices due to its rigid, conjugated framework.
• Ligand and Catalyst Development: Employed in organometallic chemistry to create novel ligands for catalysis and metal-organic frameworks (MOFs).
• Academic and Industrial R&D: A versatile scaffold for chemical biology studies, library synthesis for high-throughput screening, and process chemistry optimization.
• Fine Chemical Production: Utilized in the custom synthesis of specialty chemicals, dyes, and photographic sensitizers.

Basic Information

Product Name	7-(Chloromethyl)-3-Methyl-5H-[1,3]Thiazolo[3,2-A]Pyrimidin-5-One
CAS No.	100003-81-4
Molecular Formula	C8H7ClN2OS
Molecular Weight	214.67 g/mol
Synonyms	3-Methyl-7-(chloromethyl)-5H-[1,3]thiazolo[3,2-a]pyrimidin-5-one; 7-(Chloromethyl)-3-methyl[1,3]thiazolo[3,2-a]pyrimidin-5-one; Thiazolo[3,2-a]pyrimidin-5-one, 7-(chloromethyl)-3-methyl-; 100003-81-4; 3-Methyl-7-chloromethyl-5H-thiazolo[3,2-a]pyrimidin-5-one
EINECS	Contact for details

Quality Control

Our production of 7-(Chloromethyl)-3-Methyl-5H-[1,3]Thiazolo[3,2-A]Pyrimidin-5-One adheres to stringent quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and residual solvent analysis by GC. We provide detailed Certificates of Analysis (COA) with every shipment, ensuring traceability and compliance with customer-specific requirements and cGMP standards where applicable.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and light-sensitive; containers must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) to prevent degradation and moisture absorption.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH Q3C guidelines
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.