Description

n-Acetyl-D-Ala-D-Ala is a specialized dipeptide derivative featuring a terminal acetyl group. This compound is a critical intermediate and research tool in the fields of biochemistry and pharmaceutical development, particularly in the study of bacterial cell wall synthesis and enzyme inhibition. It is essential for researchers and manufacturers in the pharmaceutical, biotechnology, and fine chemical sectors who require high-purity, well-characterized biochemical building blocks for synthesis and screening applications.

Application

• Biochemical Research: A key substrate and intermediate for studying the mechanism of action of enzymes like D-alanyl-D-alanine carboxypeptidase and transpeptidase, which are involved in bacterial peptidoglycan synthesis.
• Antibiotic Development: Used as a core scaffold or competitive inhibitor in the research and development of novel antibiotics, particularly those targeting cell wall biosynthesis (e.g., vancomycin-related compounds).
• Enzyme Assays: Serves as a standard or substrate in high-throughput screening (HTS) assays to identify and characterize new antimicrobial agents or enzyme modulators.
• Peptide Synthesis: Acts as a protected dipeptide building block in solid-phase and solution-phase peptide synthesis for creating more complex peptide structures.
• Microbiology Studies: Utilized in research to understand bacterial resistance mechanisms, particularly those related to alterations in peptidoglycan precursor pathways.
• Reference Standard: Employed as a chromatographic or spectroscopic reference standard in analytical laboratories for quality control and method development.

Basic Information

Product Name	n-Acetyl-D-Ala-D-Ala
CAS No.	19993-26-1
Molecular Formula	C10H17N3O5
Molecular Weight	259.26 g/mol
Synonyms	Ac-D-Ala-D-Ala; N-Acetyl-D-alanyl-D-alanine; D-Alanyl-D-alanine N-acetyl; N-Acetyl-D-alanyl-D-alanine; N-Acetyl-D-alanine-D-alanine; Ac-D-Ala-D-Ala-OH; Ac-D-Ala-D-Ala; N-Acetyl-D-alanyl-D-alanine
EINECS	Contact for details

Quality Control

Every batch of n-Acetyl-D-Ala-D-Ala is produced and tested under strict quality management protocols to ensure identity, purity, and consistency suitable for research and development applications. Our products undergo rigorous quality testing, including advanced chromatographic and spectroscopic methods, to ensure compliance with stringent in-house specifications. Certificates of Analysis (COA) detailing batch-specific results are available upon request to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent product degradation or clumping. For long-term storage, consider desiccants or inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Optical Rotation	Contact for details
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.