Description

(E)-6-Aminohex-2-Enoic Acid Hydrochloride is a high-purity, protected amino acid derivative essential for advanced organic synthesis. This compound matters as a critical chiral building block, offering a reactive amine group and an unsaturated carbon-carbon bond for selective functionalization and peptide backbone modification. It is primarily needed by researchers and manufacturers in the pharmaceutical and biotechnology sectors for developing novel active pharmaceutical ingredients (APIs), peptide mimetics, and specialized biochemical probes.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the synthesis of novel drug candidates, particularly in oncology and metabolic disease research.
• Peptide Chemistry: Used in solid-phase and solution-phase peptide synthesis (SPPS) to incorporate an unsaturated, conformationally constrained amino acid residue into peptide chains.
• Bioconjugation: Serves as a linker or spacer molecule for attaching functional groups, labels (e.g., fluorophores), or drugs to biomolecules like proteins or antibodies.
• Chemical Biology Probes: Employed in the development of activity-based probes (ABPs) and other tools to study enzyme function and protein-protein interactions.
• Material Science: Potential monomer for creating specialized polymers with unique mechanical or bioactive properties.
• Academic & Industrial R&D: Fundamental building block for methodological development in organic synthesis and medicinal chemistry.

Basic Information

Product Name	(E)-6-Aminohex-2-Enoic Acid Hydrochloride
CAS No.	19991-88-9
Molecular Formula	C6H12ClNO2
Molecular Weight	165.62 g/mol
Synonyms	(2E)-6-Amino-2-hexenoic acid hydrochloride; trans-6-Amino-2-hexenoic acid hydrochloride; (E)-6-Aminohex-2-enoic acid HCl; 6-Amino-trans-2-hexenoic acid hydrochloride; Fmoc-Dap-OH(Boc) precursor; Unsaturated 6-aminohex-2-enoic acid HCl; Protected 6-amino-2-hexenoate hydrochloride
EINECS	Contact for details

Quality Control

Our (E)-6-Aminohex-2-Enoic Acid Hydrochloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity, chiral analysis, and NMR for structural confirmation, to ensure it meets the high standards required for pharmaceutical R&D and production. Certificates of Analysis (COA) with detailed chromatographic data are provided for every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C (refrigerated) for long-term stability. This product is hygroscopic (moisture-sensitive) and should be handled under a dry inert atmosphere (e.g., nitrogen or argon) when opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity	≥ 99.0% ee
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.