Description

Cyclo(-Val-Val) CAS NO 19943-16-9 is a high-purity, synthetic cyclic dipeptide composed of two valine amino acids. This compound serves as a critical building block and chiral intermediate in advanced pharmaceutical synthesis and biochemical research. It is primarily utilized by pharmaceutical R&D teams, peptide chemistry specialists, and manufacturers of fine chemicals seeking reliable, high-quality raw materials.

Application

• Pharmaceutical Intermediate: Key chiral synthon for the development of novel active pharmaceutical ingredients (APIs) and peptide-based therapeutics.
• Biochemical Research: Used as a model compound in studies of peptide conformation, cyclization mechanisms, and enzyme-substrate interactions.
• Protease Inhibitor Scaffold: Serves as a core structure in the design and synthesis of selective enzyme inhibitors.
• Fine Chemical Synthesis: Employed in the production of specialized catalysts, ligands, and advanced materials requiring specific stereochemistry.
• Reference Standard: Provides a high-purity standard for analytical method development and quality control in peptide manufacturing.

Basic Information

Product Name	Cyclo(-Val-Val)
CAS No.	19943-16-9
Molecular Formula	C10H18N2O2
Molecular Weight	198.26 g/mol
Synonyms	Cyclo(L-valyl-L-valyl); Cyclo(valyl-valine); (3S,6S)-3,6-Diisopropyl-2,5-piperazinedione; (S,S)-Cyclo(valine-valine); L-Valyl-L-valine anhydride; DKPI; Diketopiperazine of valine; 2,5-Diketopiperazine, 3,6-bis(1-methylethyl)-, (3S,6S)-
EINECS	Contact for details

Quality Control

Our Cyclo(-Val-Val) is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and chiral analysis to ensure stereochemical integrity. We provide full traceability and Certificates of Analysis (COA) are available upon request, detailing all relevant specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); ensure the container is kept tightly sealed in a low-humidity environment to maintain stability and prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity	≥ 99.0% (S,S isomer)
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.