Description

3-Fluoro-L-Phenylalanine is a fluorinated derivative of the essential amino acid L-phenylalanine, distinguished by the strategic substitution of a fluorine atom at the 3-position of the aromatic ring. This modification significantly alters its physicochemical and biological properties, making it a critical building block in advanced pharmaceutical and biochemical research. It is primarily utilized by industries focused on developing novel therapeutic agents, diagnostic tools, and specialized biochemical probes. The compound's unique structure enables its application in peptide synthesis, enzyme studies, and as a precursor for more complex fluorinated molecules.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of fluorinated peptide-based drugs and active pharmaceutical ingredients (APIs).
• Biochemical Research: Used in enzyme inhibition studies, metabolic pathway analysis, and as a non-natural amino acid in protein engineering.
• PET (Positron Emission Tomography) Tracer Development: Serves as a precursor for F-18 labeled radiopharmaceuticals used in medical imaging.
• Peptide Synthesis: Incorporated into custom peptides to enhance stability, modulate bioavailability, or introduce specific biological activity.
• Agrochemical Research: Investigated as a component in the development of novel herbicides and plant growth regulators.
• Academic & Industrial R&D: Fundamental research tool in medicinal chemistry and chemical biology for structure-activity relationship (SAR) studies.

Basic Information

Item	Detail
Product Name	3-Fluoro-L-Phenylalanine
CAS No.	19883-77-3
Molecular Formula	C9H10FNO2
Molecular Weight	183.18 g/mol
Synonyms	(S)-2-Amino-3-(3-fluorophenyl)propanoic acid; L-3-Fluorophenylalanine; 3-F-DL-Phe; 3-Fluoro-L-phenylalanine; 3-F-Phe; (S)-3-Fluorophenylalanine; 3-Fluorophenylalanine, L-; F3Phe
EINECS	Contact for details

Quality Control

Our 3-Fluoro-L-Phenylalanine is manufactured under a strict quality management system. Every batch undergoes comprehensive analytical testing, including HPLC for purity, chiral analysis for enantiomeric excess, and identity confirmation via IR and NMR spectroscopy. We provide full traceability and Certificates of Analysis (COA) are available upon request, detailing all relevant specifications. Production can be aligned with cGMP guidelines for pharmaceutical applications upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% (L-Isomer)
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.