Description

6-Chloro-2-(Chloromethyl)Pyrimidin-4(3H)-One is a versatile halogenated pyrimidinone derivative that serves as a critical building block in advanced organic synthesis. Its bifunctional reactivity, featuring both a chloro and a chloromethyl group on the pyrimidine core, makes it an invaluable intermediate for constructing complex molecular architectures. This compound is primarily sought after by research and development chemists in the pharmaceutical and agrochemical industries for the synthesis of active ingredients and novel chemical entities.

Application

• Pharmaceutical Intermediate: Key synthon for the development of antiviral, anticancer, and other biologically active small molecule drugs.
• Agrochemical Synthesis: Used in the production of herbicides, fungicides, and insecticides, leveraging its halogenated structure for efficacy.
• Chemical Research & Development: Serves as a versatile scaffold in medicinal chemistry for structure-activity relationship (SAR) studies and library synthesis.
• Material Science Precursor: Potential intermediate in the synthesis of specialty polymers, ligands, or functionalized materials.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs for the production of client-specific target molecules under cGMP conditions where required.

Basic Information

Product Name	6-Chloro-2-(Chloromethyl)Pyrimidin-4(3H)-One
CAS No.	19874-98-7
Molecular Formula	C5H4Cl2N2O
Molecular Weight	179.00 g/mol
Synonyms	4(3H)-Pyrimidinone, 6-chloro-2-(chloromethyl)-; 2-(Chloromethyl)-6-chloropyrimidin-4(3H)-one; 6-Chloro-2-chloromethyl-4-hydroxypyrimidine; 6-Chloro-2-(chloromethyl)-4-pyrimidinol; 4-Hydroxy-6-chloro-2-chloromethylpyrimidine; 6-Chloro-2-chloromethyl-4(3H)-pyrimidinone; 19874-98-7
EINECS	Contact for details

Quality Control

Our 6-Chloro-2-(Chloromethyl)Pyrimidin-4(3H)-One is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via FT-IR and NMR spectroscopy, to ensure it meets the high standards required for synthetic applications. A comprehensive Certificate of Analysis (COA) detailing all test results is provided with every shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (typically 15-25°C). Keep away from strong bases and oxidizing agents. For long-term storage, consider under an inert atmosphere to maintain product integrity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.