Description

5-Pyrimidinemethanol, 2-(Methylthio)- (8Ci,9Ci) CAS NO 19858-50-5 is a specialized heterocyclic building block featuring a pyrimidine core substituted with a hydroxymethyl and a methylthio group. This compound matters as a key synthetic intermediate for the development of novel active pharmaceutical ingredients (APIs) and agrochemicals, where its unique structure enables precise molecular modifications. It is primarily needed by research and development chemists in the pharmaceutical, agrochemical, and fine chemical industries for constructing complex molecules in drug discovery and advanced material synthesis.

Application

• Pharmaceutical Intermediate: Serves as a crucial precursor in the synthesis of nucleoside analogs, antiviral agents, and other therapeutic compounds targeting various disease pathways.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and plant growth regulators, leveraging its heterocyclic scaffold for bioactivity.
• Fine Chemical Synthesis: Acts as a versatile building block for creating complex organic molecules used in material science, catalysis, and specialty polymers.
• Biochemical Research: Employed in the study of enzyme inhibitors and as a molecular probe to investigate biological processes involving pyrimidine metabolism.
• Academic & Industrial R&D: Essential for medicinal chemistry programs and process development in both university laboratories and corporate R&D centers.

Basic Information

Product Name	5-Pyrimidinemethanol, 2-(Methylthio)- (8Ci,9Ci)
CAS No.	19858-50-5
Molecular Formula	C6H8N2OS
Molecular Weight	156.20 g/mol
Synonyms	2-(Methylthio)-5-pyrimidinemethanol; (2-Methylsulfanylpyrimidin-5-yl)methanol; 5-(Hydroxymethyl)-2-(methylthio)pyrimidine; 2-Methylmercapto-5-pyrimidinemethanol; 2-Methylthio-5-pyrimidinemethanol; 2-(Methylsulfanyl)-5-pyrimidinemethanol; 2-(Methylthio)pyrimidine-5-methanol
EINECS	Contact for details

Quality Control

Our 5-Pyrimidinemethanol, 2-(Methylthio)- is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and NMR for structural confirmation, to ensure it meets the high standards required for research and development applications. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.