Description

5-Bromo-1H-Pyrimidin-4-One is a versatile brominated heterocyclic building block of significant importance in advanced organic synthesis. Its core value lies in its reactivity as a key intermediate for constructing complex molecular architectures, particularly in pharmaceutical research and development. This compound is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for creating novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Serves as a crucial precursor in the synthesis of novel drug candidates, including kinase inhibitors, antiviral agents, and other biologically active molecules.
• Agrochemical Synthesis: Used in the research and development of new herbicides, fungicides, and plant growth regulators.
• Material Science: Acts as a building block for creating specialized polymers, ligands for catalysis, and organic electronic materials.
• Chemical Biology & Proteomics: Employed in the design and synthesis of molecular probes, tags, and inhibitors for studying biological systems.
• Custom Synthesis & Contract Manufacturing: A key starting material for custom synthesis projects and scale-up processes in fine chemical production.
• Academic & Institutional Research: Utilized in universities and research institutes for methodological development and exploratory chemistry.

Basic Information

Product Name	5-Bromo-1H-Pyrimidin-4-One
CAS No.	19808-30-1
Molecular Formula	C4H3BrN2O
Molecular Weight	174.98 g/mol
Synonyms	5-Bromo-4-hydroxypyrimidine; 5-Bromo-4(1H)-pyrimidinone; 4-Hydroxy-5-bromopyrimidine; 5-Bromo-1H-pyrimidin-4-ol; 5-Bromo-4-pyrimidinol; 5-Bromopyrimidin-4-ol; 5-Bromo-4(3H)-pyrimidinone; 19808-30-1
EINECS	Contact for details

Quality Control

Our 5-Bromo-1H-Pyrimidin-4-One is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all relevant specifications. Our quality commitment supports applications requiring high-purity intermediates for research and development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place. Recommended storage temperature is 2-8°C for long-term stability. The compound may be light-sensitive and should be handled under appropriate conditions to maintain purity.

Specification

Item	Specification
Appearance	White to off-white powder/crystals
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Assay (HPLC)	≥97.0%
Purity (HPLC Area %)	≥98.0%
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.