Description

H-D-Ser(So3H)-Oh is a modified amino acid derivative, specifically the sulfonated form of D-serine. This compound is a valuable chiral building block and biochemical reagent, prized for its role in modulating N-methyl-D-aspartate (NMDA) receptor function and related neurological research. It is essential for researchers and manufacturers in the pharmaceutical, biotechnology, and advanced life science sectors who require high-purity, specialized intermediates for peptide synthesis and neurochemical studies.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the development of novel neuroactive drugs and peptide-based therapeutics targeting the central nervous system.
• Biochemical Research: Used as a reference standard and active agent in studies of NMDA receptor pharmacology, synaptic plasticity, and neurological disorders.
• Peptide Synthesis: Incorporated into custom peptides to introduce sulfonate functionality, altering solubility, stability, and biological activity.
• Proteomics & Cell Signaling Studies: Serves as a tool compound to investigate phosphorylation-mimicking effects and protein-protein interactions in signal transduction pathways.
• Diagnostic Reagent Development: Potential use in the formulation of assays and kits for neurological biomarker detection and research.

Basic Information

Product Name	H-D-Ser(So3H)-Oh
CAS No.	19794-48-0
Molecular Formula	C3H7NO6S
Molecular Weight	185.16 g/mol
Synonyms	D-Serine, O-sulfonated; (R)-2-Amino-3-hydroxypropanoic acid 3-sulfonate; D-Serine sulfonic acid; H-D-Ser(SO3H)-OH; D-Serine O-sulfate; (R)-Serine O-sulfonic acid; D-3-Sulfonoalanine; D-Serine sulfuric acid
EINECS	Contact for details

Quality Control

Our H-D-Ser(So3H)-Oh is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, chiral analysis to confirm the D-configuration, and identity confirmation via IR and NMR. We provide full traceability and Certificates of Analysis (COA) are available for all shipments, ensuring compliance with research and development grade specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a desiccated environment to prevent degradation. For long-term storage, consider inert atmosphere conditions.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% D-isomer
Water Content (KF)	≤ 2.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.