Description

n-Benzoylhistidine is a chemically modified derivative of the essential amino acid L-histidine, where the benzoyl group provides enhanced stability and specific functional properties. This compound is valued for its role as a key synthetic intermediate and building block in advanced pharmaceutical and biochemical research. It is primarily utilized by manufacturers and R&D laboratories in the pharmaceutical, peptide synthesis, and life science sectors for developing novel therapeutic agents and biochemical tools.

Application

• Pharmaceutical Intermediate: A crucial building block in the synthesis of complex drug molecules and active pharmaceutical ingredients (APIs).
• Peptide Synthesis: Used in solid-phase and solution-phase peptide synthesis to incorporate modified histidine residues into peptide chains.
• Biochemical Research: Serves as a substrate or inhibitor in enzymatic studies and as a standard in analytical method development.
• Protecting Group Chemistry: The benzoyl moiety can act as a protecting group for the imidazole side chain of histidine during multi-step organic syntheses.
• Reference Standard: Employed as a high-purity chemical reference standard in quality control laboratories for HPLC, LC-MS, or NMR analysis.

Basic Information

Product Name	n-Benzoylhistidine
CAS No.	19785-88-7
Molecular Formula	C13H13N3O3
Molecular Weight	259.26 g/mol
Synonyms	Nα-Benzoyl-L-histidine; Bzl-His-OH; L-Histidine, N-benzoyl-; Benzoylated Histidine; N-Benzoyl-L-histidine; Histidine benzoyl derivative; (2S)-2-Benzamido-3-(1H-imidazol-4-yl)propanoic acid
EINECS	Contact for details

Quality Control

Our n-Benzoylhistidine is manufactured under a strict quality management system. Every batch undergoes comprehensive analytical testing, including HPLC for purity, chiral analysis, and identity confirmation (IR, NMR) to ensure it meets exacting standards for research and production. Certificates of Analysis (COA) with complete batch-specific data are provided and available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after each use to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Optical Rotation	Specific rotation provided per COA
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.