Description

5-Bromowillardiine is a potent and selective agonist for the glutamate receptor subtype GluK1 (GluR5). This compound is a crucial research tool in neuroscience, enabling the study of kainate receptor function and its role in synaptic transmission, plasticity, and neurological disorders. It is primarily utilized by pharmaceutical R&D teams, academic neuroscientists, and biochemical suppliers focused on developing and understanding novel neuropharmacological agents.

Application

• Neuroscience Research: A key pharmacological tool for selectively activating and studying GluK1 (GluR5) kainate receptors in vitro and in vivo.
• Drug Discovery & Development: Used in high-throughput screening (HTS) assays to identify and characterize potential antagonists or modulators of kainate receptors for therapeutic applications.
• Neuropharmacology Studies: Investigating the role of kainate receptors in pain pathways, epilepsy, migraine, and neurodegenerative diseases.
• Signal Transduction Research: Elucidating downstream signaling cascades and cellular responses triggered by specific glutamate receptor activation.
• Biochemical Reagent: Serves as a reference standard and active ingredient in the preparation of specialized biochemical kits and research reagents.

Basic Information

Product Name	5-Bromowillardiine
CAS No.	19772-78-2
Molecular Formula	C7H6BrN3O4
Molecular Weight	276.04 g/mol
Synonyms	5-Bromo-DL-willardiine; (S)-2-Amino-3-(5-bromo-2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)propanoic acid; 5-Bromouracil-1-yl-L-alanine; Bromowillardiine; GluK1 agonist; GluR5 agonist; NSC 339313
EINECS	Contact for details

Quality Control

Our 5-Bromowillardiine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via NMR and MS, to ensure it meets the high standards required for critical research applications. A detailed Certificate of Analysis (COA) is provided with every shipment, guaranteeing traceability and consistent quality.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C. This product is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥98.0%
Water Content (KF)	≤1.0%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.