Description

2-Acetamido-3-Methyl-Pentanoic Acid is a specialized chiral amino acid derivative with significant utility in advanced organic synthesis. Its value lies in its role as a key building block for constructing complex peptide mimetics and pharmaceutical intermediates, offering precise stereochemical control. This compound is primarily needed by research institutions and manufacturers in the pharmaceutical, biotechnology, and fine chemical sectors for developing novel therapeutic agents and bioactive compounds.

Application

• Pharmaceutical Intermediate: A crucial chiral synthon for the synthesis of novel peptide-based drugs and enzyme inhibitors.
• Biochemical Research: Used in proteomics and metabolic pathway studies as a modified amino acid probe.
• Peptidomimetic Development: Serves as a building block for creating non-natural peptides with enhanced stability and bioavailability.
• Asymmetric Synthesis: Employed as a starting material or auxiliary in catalytic asymmetric reactions to introduce chiral centers.
• Fine Chemical Production: Integral in the manufacture of specialty chemicals, including advanced ligands and catalysts.
• Reference Standard: Utilized as a high-purity analytical standard in quality control laboratories for method development and validation.

Basic Information

Product Name	2-Acetamido-3-Methyl-Pentanoic Acid
CAS No.	19764-31-9
Molecular Formula	C8H15NO3
Molecular Weight	173.21 g/mol
Synonyms	N-Acetyl-3-methylnorvaline; 3-Methyl-2-acetamidopentanoic acid; (2R,3S)-2-Acetamido-3-methylpentanoic acid (and other stereoisomers); N-Acetyl-3-methyl-2-aminopentanoic acid; 2-(Acetylamino)-3-methylpentanoic acid; Ac-3-MeNva-OH; α-Acetamido-β-methylvaleric acid
EINECS	Contact for details

Quality Control

Our 2-Acetamido-3-Methyl-Pentanoic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity assessment by HPLC, to ensure it meets the high standards required for research and synthesis. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to guarantee traceability and compliance.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after use to prevent moisture absorption, which may affect stability and handling properties.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% ee (specify isomer)
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.