Description

2,4-Di-(tert-Butoxy)-5-Bromopyrimidine is a high-value, multi-functional brominated pyrimidine derivative. This compound matters as a versatile and protected synthetic intermediate, enabling the precise construction of complex molecules in advanced research and manufacturing. It is primarily needed by pharmaceutical R&D teams and fine chemical manufacturers for the development of active pharmaceutical ingredients (APIs), agrochemicals, and specialty materials.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of nucleoside analogs, antiviral agents, and other bioactive heterocyclic compounds.
• Agrochemical Synthesis: Used in the research and production of novel herbicides, fungicides, and plant growth regulators.
• Material Science Research: Serves as a precursor for creating functionalized polymers, liquid crystals, and organic electronic materials.
• Cross-Coupling Reactions: The bromine atom makes it an excellent substrate for Suzuki, Stille, and other palladium-catalyzed cross-coupling reactions to form new carbon-carbon bonds.
• Chemical Biology & Proteomics: Employed in the design and synthesis of molecular probes, enzyme inhibitors, and labeled compounds for biological studies.
• Custom Synthesis & Contract Manufacturing: A critical starting material for custom synthesis projects requiring protected, halogenated pyrimidine scaffolds.

Basic Information

Product Name	2,4-Di-(tert-Butoxy)-5-Bromopyrimidine
CAS No.	19752-61-5
Molecular Formula	C12H19BrN2O2
Molecular Weight	303.20 g/mol
Synonyms	5-Bromo-2,4-di-tert-butoxypyrimidine; 2,4-Bis(tert-butoxy)-5-bromopyrimidine; 5-Bromo-2,4-bis(tert-butoxy)pyrimidine; 5-Bromo-2,4-di-O-tert-butylpyrimidine; 19752-61-5; tert-Butyl 5-bromo-2,4-dioxo-1,2,3,4-tetrahydropyrimidine-1-carboxylate (tautomer); Brominated pyrimidine ether
EINECS	Contact for details

Quality Control

Our 2,4-Di-(tert-Butoxy)-5-Bromopyrimidine is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and NMR for structural confirmation, to ensure it meets the high standards required for research and synthesis. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.