Description

S-(Acetamidomethyl)-L-Cysteine is a protected cysteine derivative, a crucial building block in peptide synthesis and pharmaceutical research. Its primary value lies in its role as a thiol-protecting group, preventing unwanted side reactions during the complex assembly of peptide chains. This compound is essential for researchers and manufacturers in the pharmaceutical, biotechnology, and fine chemical industries developing novel peptide-based therapeutics and biochemical tools.

Application

• Solid-Phase Peptide Synthesis (SPPS): A key reagent for the controlled incorporation of cysteine residues, protecting the thiol group from oxidation or disulfide formation during synthesis.
• Pharmaceutical Intermediates: Serves as a critical intermediate in the production of complex peptide drugs, including hormones, enzyme inhibitors, and antiviral agents.
• Bioconjugation Chemistry: Used to introduce protected thiol handles onto biomolecules for subsequent site-specific labeling or cross-linking.
• Research & Development: A fundamental tool in academic and industrial R&D for studying protein structure-function relationships and developing new synthetic methodologies.
• Production of Cysteine Analogs: Acts as a precursor for synthesizing various modified cysteine derivatives with tailored properties.

Basic Information

Product Name	S-(Acetamidomethyl)-L-Cysteine
CAS No.	19647-70-2
Molecular Formula	C6H12N2O3S
Molecular Weight	192.23 g/mol
Synonyms	L-Cysteine, S-(acetamidomethyl)-; Acetamidomethyl-L-cysteine; AMM-L-Cys; S-(Acetamidomethyl)cysteine; (2R)-2-Amino-3-[[(acetylamino)methyl]sulfanyl]propanoic acid; N-Acetamidomethyl-L-cysteine; S-Acetamidomethyl-L-cysteine; AAMC
EINECS	243-190-2

Quality Control

Our S-(Acetamidomethyl)-L-Cysteine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, chiral analysis, and residual solvent screening, to ensure it meets the stringent requirements for peptide synthesis. Certificates of Analysis (COA) with detailed specifications are provided for every shipment, ensuring full traceability and compliance with relevant industry standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 15-25°C. This product is hygroscopic (moisture-sensitive); ensure the container is kept tightly sealed in a low-humidity environment to maintain stability and prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Optical Rotation [α]20/D	-20.0° to -24.0° (c=1 in 1N HCl)
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.