Description

Z-o-Acetyl-L-Serine is a chemically modified derivative of the amino acid L-serine, featuring an acetyl group protecting the hydroxyl side chain. This modification is critical for its primary role as a key chiral building block and intermediate in the synthesis of complex peptides, pharmaceuticals, and fine chemicals. It is essential for researchers and manufacturers in the pharmaceutical, biotechnology, and advanced organic synthesis sectors who require high-purity, stereochemically defined intermediates for developing active pharmaceutical ingredients (APIs) and other bioactive compounds.

Application

• Pharmaceutical Intermediate: A crucial building block in the synthesis of peptide-based drugs, antibiotics, and other therapeutic agents.
• Peptide Synthesis: Used in solid-phase and solution-phase peptide synthesis to incorporate serine residues with a protected side chain, preventing unwanted side reactions.
• Bioconjugation & Labeling: Serves as a starting material for creating modified amino acids used in bioconjugation chemistry for drug delivery systems or diagnostic probes.
• Biochemical Research: Employed in enzymatic studies and as a substrate or inhibitor in metabolic pathway research.
• Fine Chemical Synthesis: An intermediate in the production of chiral catalysts, ligands, and other specialty organic compounds.
• Cosmetic Peptides: Potential use as a precursor in the synthesis of bioactive peptides for cosmetic and dermatological applications.

Basic Information

Product Name	Z-o-Acetyl-L-Serine
CAS No.	19645-29-5
Molecular Formula	C₁₄H₁₇NO₆
Molecular Weight	295.29 g/mol
Synonyms	N-Carbobenzoxy-O-acetyl-L-serine; Z-L-Ser(Ac)-OH; N-(Benzyloxycarbonyl)-O-acetyl-L-serine; (2S)-2-[[(Benzyloxy)carbonyl]amino]-3-acetyloxypropanoic acid; CBZ-O-acetyl-L-serine; Nα-Cbz-O-acetyl-L-serine; L-Serine, N-[(phenylmethoxy)carbonyl]-, 3-acetate; Benzyl N-[(2S)-2-carboxy-1-(acetyloxy)ethyl]carbamate
EINECS	Contact for details

Quality Control

Our Z-o-Acetyl-L-Serine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, chiral analysis to confirm stereochemical integrity, and identification via IR and NMR spectroscopy. We provide a Certificate of Analysis (COA) with each shipment, detailing all specifications and test results to ensure compliance with your research or cGMP-grade requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider desiccants or inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Optical Rotation [α]²⁰D	-15.0° to -18.0° (c=1 in DMF)
Chiral Purity (HPLC)	≥99.0%
Water Content (KF)	≤1.0%
Residue on Ignition	≤0.1%
Heavy Metals	≤10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.