Description

5-Chloro-4,6-Dimethyl-1H-Pyrimidin-2-One is a high-purity, versatile heterocyclic building block essential for advanced organic synthesis. This compound serves as a critical intermediate in the development of active pharmaceutical ingredients (APIs) and agrochemicals, where its specific substitution pattern enables precise molecular modifications. It is primarily sought after by research institutions and industrial manufacturers in the pharmaceutical, agrochemical, and fine chemical sectors for creating novel compounds with targeted biological activity.

Application

• Pharmaceutical Intermediate: A key synthon in the synthesis of nucleoside analogs, antiviral agents, and other therapeutic molecules.
• Agrochemical Synthesis: Used in the research and production of herbicides, fungicides, and plant growth regulators.
• Fine Chemical Production: Serves as a building block for dyes, pigments, and advanced materials requiring specific pyrimidine scaffolds.
• Academic & Industrial R&D: Employed in medicinal chemistry and chemical biology for structure-activity relationship (SAR) studies and library synthesis.
• Ligand and Catalyst Development: Potential precursor for creating specialized ligands used in catalytic systems.

Basic Information

Product Name	5-Chloro-4,6-Dimethyl-1H-Pyrimidin-2-One
CAS No.	19573-82-1
Molecular Formula	C6H7ClN2O
Molecular Weight	158.59 g/mol
Synonyms	5-Chloro-4,6-dimethyl-2(1H)-pyrimidinone; 5-Chloro-4,6-dimethylpyrimidin-2(1H)-one; 4,6-Dimethyl-5-chloro-2-hydroxypyrimidine; 2-Hydroxy-4,6-dimethyl-5-chloropyrimidine; 5-Chloro-4,6-dimethyl-1H-pyrimidin-2-ol; 5-Chloro-4,6-dimethyl-2-pyrimidinol
EINECS	Contact for details

Quality Control

Our 5-Chloro-4,6-Dimethyl-1H-Pyrimidin-2-One is manufactured under a strict quality management system. Every batch undergoes comprehensive analytical testing, including HPLC, NMR, and GC-MS, to ensure identity, purity, and consistency. A Certificate of Analysis (COA) detailing all specifications is provided with each shipment. We support compliance with REACH and other global regulatory frameworks.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.