Description

Z-Val-Phe-Oh is a protected dipeptide building block, specifically the Z-protected derivative of the Val-Phe sequence. This compound is a critical intermediate in the synthesis of complex peptides and peptidomimetics, offering controlled coupling and deprotection steps. It is primarily utilized by research institutions and pharmaceutical companies engaged in the development of therapeutic peptides, protease inhibitors, and biochemical tools.

Application

• Solid-Phase Peptide Synthesis (SPPS): A key protected fragment for the sequential assembly of longer peptide chains.
• Pharmaceutical Intermediates: Serves as a building block in the research and production of active pharmaceutical ingredients (APIs) for peptide-based drugs.
• Biochemical Research: Used in studies of enzyme-substrate interactions, particularly with proteases like renin and angiotensin-converting enzyme (ACE).
• Peptidomimetic Development: Acts as a core structure for designing and synthesizing non-peptide compounds that mimic peptide bioactivity.
• Custom Peptide Services: A standard offering for fine chemical suppliers providing bespoke peptide synthesis for clients.

Basic Information

Product Name	Z-Val-Phe-Oh
CAS No.	19542-51-9
Molecular Formula	C24H30N2O5
Molecular Weight	426.51 g/mol
Synonyms	N-Carbobenzoxy-L-valyl-L-phenylalanine; Z-L-Valyl-L-phenylalanine; Z-Val-Phe-OH; Benzyloxycarbonyl-L-valyl-L-phenylalanine; Cbz-Val-Phe-OH; Nα-(Benzyloxycarbonyl)-L-valyl-L-phenylalanine; (S)-2-(((Benzyloxy)carbonyl)amino)-3-methyl-N-((S)-1-oxo-3-phenyl-1-(phenylamino)propan-2-yl)butanamide; L-Phenylalanine, N-[(benzyloxy)carbonyl]-L-valyl-
EINECS	Contact for details

Quality Control

Our Z-Val-Phe-Oh is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, chiral analysis for enantiomeric excess, and identity confirmation via IR and NMR spectroscopy. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment to ensure traceability and batch-to-batch consistency for your critical research and development projects.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.