Description

Z-D-Ala-Phe-Oh is a protected dipeptide derivative, specifically the benzyloxycarbonyl (Z) protected form of D-alanyl-L-phenylalanine. This compound is a crucial chiral building block in the synthesis of complex peptides and peptidomimetics, offering precise stereochemical control. It is primarily utilized by research institutions and pharmaceutical companies engaged in the development of novel therapeutic agents, diagnostic tools, and biochemical research reagents.

Application

• Pharmaceutical Intermediate: Key chiral synthon for the solid-phase and solution-phase synthesis of peptide-based drugs and active pharmaceutical ingredients (APIs).
• Biochemical Research: Used as a standard or building block in studies of enzyme specificity, peptide structure-activity relationships (SAR), and metabolic pathways.
• Proteomics & Diagnostics: Employed in the development of specialized substrates for proteases or as components in diagnostic assay kits.
• Academic & R&D: Serves as a fundamental reagent in university and industrial laboratories for organic synthesis and medicinal chemistry projects.
• Peptidomimetic Design: Acts as a core structure for creating non-natural peptide analogs with enhanced stability or biological activity.

Basic Information

Product Name	Z-D-Ala-Phe-Oh
CAS No.	19542-44-0
Molecular Formula	C20H22N2O5
Molecular Weight	370.40 g/mol
Synonyms	N-[(Benzyloxy)carbonyl]-D-alanyl-L-phenylalanine; Z-D-Ala-L-Phe-OH; Cbz-D-Ala-L-Phe-OH; N-Carbobenzoxy-D-alanyl-L-phenylalanine; Benzyl N-[(2S)-1-[[(2R)-2-aminopropanoyl]amino]-3-phenyl-1-oxopropan-2-yl]carbamate; D-Alanine, N-[(benzyloxy)carbonyl]-, L-phenylalanine deriv.; Z-D-Ala-Phe; CBZ-D-Alanine-L-Phenylalanine
EINECS	Contact for details

Quality Control

Our Z-D-Ala-Phe-Oh is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and chiral integrity, to ensure it meets high-grade research and development specifications. Certificates of Analysis (COA) with detailed chromatographic data are available upon request to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption, which can affect stability and handling properties.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.