Description

Ac-D-Ala-Oh CAS NO 19436-52-3 is a high-purity, N-acetylated derivative of the D-enantiomer of the amino acid alanine. This protected amino acid building block is essential for the synthesis of complex peptides with specific stereochemistry and enhanced metabolic stability. It is primarily utilized by research institutions and pharmaceutical companies engaged in advanced peptide chemistry and drug discovery. The compound's defined chiral center makes it a critical reagent for developing novel therapeutic agents and biochemical tools.

Application

• Pharmaceutical Intermediate: A key chiral building block in the solid-phase and solution-phase synthesis of therapeutic peptides and peptidomimetics.
• Biochemical Research: Used in studies of enzyme specificity, peptide structure-activity relationships (SAR), and chiral molecular recognition.
• Antibiotic Development: Serves as a precursor in the synthesis of certain antibiotic compounds that incorporate D-amino acids for resistance to enzymatic degradation.
• Cosmetic Peptides: Incorporated into the synthesis of bioactive peptides for cosmetic applications, such as anti-aging or skin-repair formulations.
• Reference Standard: Employed as a high-purity analytical standard for quality control and method development in chromatographic analysis.

Basic Information

Product Name	Ac-D-Ala-Oh
CAS No.	19436-52-3
Molecular Formula	C5H9NO3
Molecular Weight	131.13 g/mol
Synonyms	N-Acetyl-D-alanine; (R)-2-Acetamidopropanoic acid; D-α-Acetamidopropionic acid; Ac-D-Ala-OH; N-Acetyl-D-alanine; Ac-D-Ala; N-Acetyl-(R)-alanine; D-N-Acetylalanine
EINECS	243-093-8

Quality Control

Our Ac-D-Ala-Oh is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity verification by HPLC, to ensure it meets the high standards required for pharmaceutical research and development. Certificates of Analysis (COA) detailing purity, specific rotation, and impurity profiles are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept in a desiccated environment to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Chiral Purity (HPLC)	≥99.0% D-isomer
Specific Rotation [α]20/D	-40.0° to -44.0° (c=1 in H2O)
Loss on Drying	≤0.5%
Residue on Ignition	≤0.1%
Heavy Metals (as Pb)	≤10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.