Description

Acth (1-4) CAS NO 19405-50-6 is a synthetic tetrapeptide fragment of the adrenocorticotropic hormone (ACTH). This compound is of significant interest in biochemical research and pharmaceutical development due to its role in studying melanocortin receptor activity and related physiological pathways. It is primarily utilized by research institutions and pharmaceutical companies engaged in peptide synthesis, neuroendocrinology, and the development of novel therapeutic agents.

Application

• Biochemical Research: Used as a reference standard and tool compound for studying the structure-activity relationships (SAR) of ACTH and melanocortin peptides.
• Pharmaceutical R&D: Serves as a key intermediate or active pharmaceutical ingredient (API) in the development of peptide-based therapeutics targeting melanocortin receptors.
• Academic Studies: Employed in university and institutional labs for investigating hormone signaling, peptide-receptor interactions, and metabolic regulation.
• Diagnostic Development: Potential use in the formulation of diagnostic kits or assays related to adrenal function and endocrine disorders.
• Peptide Library Synthesis: A building block for constructing combinatorial peptide libraries for high-throughput screening in drug discovery.

Basic Information

Product Name	Acth (1-4)
CAS No.	19405-50-6
Molecular Formula	C24H35N7O6
Molecular Weight	517.58 g/mol
Synonyms	ACTH (1-4); Adrenocorticotropic Hormone (1-4); H-Ser-Tyr-Ser-Met-OH; Ser-Tyr-Ser-Met; Tetracosactide fragment 1-4; Melanotropin (1-4); Corticotropin (1-4); ACTH1-4
EINECS	Contact for details

Quality Control

Our Acth (1-4) is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, MS for identity confirmation, and tests for residual solvents and related substances. We provide full traceability and Certificates of Analysis (COA) are available for all shipments. Production can be aligned with cGMP guidelines for advanced research and development applications.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry environment. This product is hygroscopic (moisture-sensitive). Allow the vial to reach room temperature in a desiccator before opening to minimize moisture uptake. For long-term storage, consider under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC/MS)	Conforms to reference standard
Purity (HPLC)	≥ 98.0%
Single Impurity (HPLC)	≤ 1.0%
Water Content (KF)	≤ 5.0%
Peptide Content	≥ 80.0%
Acetate Content (HPIC)	≤ 10.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.