Description

4-Amino-6-Bromo-7H-Pyrrolo[2,3-D]Pyrimidine-5-Carbonitrile is a high-purity, heterocyclic organic building block of significant interest in advanced chemical synthesis. This compound serves as a critical intermediate for the development of novel pharmaceutical agents, particularly kinase inhibitors and other targeted therapeutics. It is primarily utilized by research institutions, pharmaceutical R&D departments, and fine chemical manufacturers engaged in drug discovery and process development.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of small molecule kinase inhibitors for oncology and other therapeutic areas.
• Biochemical Research: Used as a scaffold or building block in medicinal chemistry for structure-activity relationship (SAR) studies.
• Agrochemical Development: Potential intermediate for creating novel active ingredients with specific biological activity.
• Material Science Research: Exploration of organic electronic materials due to its fused pyrrolopyrimidine core structure.
• Contract Research & Manufacturing (CRO/CMO): Supplied to organizations specializing in custom synthesis and process scale-up.
• Academic Research: Utilized in university laboratories for heterocyclic chemistry and synthetic methodology development.

Basic Information

Product Name	4-Amino-6-Bromo-7H-Pyrrolo[2,3-D]Pyrimidine-5-Carbonitrile
CAS No.	19393-83-0
Molecular Formula	C7H4BrN5
Molecular Weight	238.05 g/mol
Synonyms	6-Bromo-4-amino-7H-pyrrolo[2,3-d]pyrimidine-5-carbonitrile; 4-Amino-6-bromo-5-cyano-7H-pyrrolo[2,3-d]pyrimidine; 6-Bromo-4-amino-5-cyano-7H-pyrrolo[2,3-d]pyrimidine; 19393-83-0; Pyrrolo[2,3-d]pyrimidine-5-carbonitrile, 4-amino-6-bromo-7H-; AKOS005258212; BRN 1217705; CS-W009767
EINECS	Contact for details

Quality Control

Our 4-Amino-6-Bromo-7H-Pyrrolo[2,3-D]Pyrimidine-5-Carbonitrile is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via NMR and mass spectrometry, to ensure it meets the high standards required for research and pharmaceutical development. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (typically 15-25°C). This compound may be moisture-sensitive; keep the container tightly sealed in a dry environment.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (HPLC)	Conforms
Identification (IR)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%
Single Unknown Impurity (HPLC)	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.