Description

Ac-Phe-Tyr-Nh2 is a synthetic dipeptide derivative, specifically an acetylated and amidated derivative of the phenylalanine-tyrosine sequence. This compound is a valuable building block in peptide synthesis and biochemical research, offering a protected and functionalized structure for advanced applications. It is primarily utilized by pharmaceutical R&D laboratories, biotechnology companies, and academic institutions engaged in peptide chemistry, medicinal chemistry, and proteomics studies.

Application

• Peptide Synthesis Intermediate: Serves as a key protected fragment for the solid-phase or solution-phase synthesis of longer, more complex peptide chains.
• Biochemical Research: Used as a standard or reference compound in studies of enzyme kinetics, substrate specificity, and protein-protein interactions.
• Medicinal Chemistry: Acts as a core scaffold or precursor for the development of novel peptide-based therapeutics and diagnostic agents.
• Protease Substrate Analog: Employed in enzymatic assays to study the activity and inhibition of proteases like chymotrypsin or carboxypeptidases.
• Pharmaceutical Impurity Standard: Used as a certified reference material (CRM) for quality control and analytical method development in drug manufacturing.

Basic Information

Product Name	Ac-Phe-Tyr-Nh2
CAS No.	19361-52-5
Molecular Formula	C20H23N3O5
Molecular Weight	385.42 g/mol
Synonyms	N-Acetyl-L-phenylalanyl-L-tyrosinamide; Acetyl-Phenylalanyl-Tyrosine Amide; Ac-Phe-Tyr-NH2; L-Phenylalanine, N-acetyl-L-tyrosinamide; N-Acetylphenylalanylyrosinamide; Acetylphenylalanyltyrosinamide; H-Ac-Phe-Tyr-NH2
EINECS	Contact for details

Quality Control

Our Ac-Phe-Tyr-Nh2 is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC for purity, chiral analysis, and identity confirmation via mass spectrometry (MS) and infrared (IR) spectroscopy. We provide a detailed Certificate of Analysis (COA) with every shipment, ensuring traceability and compliance with your research or development specifications. Custom purity grades, including research and pharmaceutical intermediates, are available.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive); ensure the container is sealed after each use to prevent degradation from atmospheric moisture. For long-term storage, consider desiccants or inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (MS)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Specific Rotation	Contact for details
Water Content (KF)	≤ 1.0%
Heavy Metals	< 10 ppm
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.