Description

H-Gly-Nva-Oh CAS NO 19257-03-5 is a high-purity, protected dipeptide building block essential for advanced peptide synthesis. This compound serves as a critical intermediate for constructing complex peptide sequences with precise control over structure and function. It is primarily utilized by research institutions and pharmaceutical companies engaged in the development of novel therapeutic peptides, diagnostic agents, and biochemical tools.

Application

• Pharmaceutical Research & Development: A key intermediate in the solid-phase and solution-phase synthesis of potential therapeutic peptides targeting various diseases.
• Peptide Library Construction: Used in combinatorial chemistry to create diverse peptide libraries for high-throughput screening and drug discovery.
• Bioconjugation & Probe Synthesis: Serves as a spacer or linker component in the synthesis of peptide-based probes, labels, and antibody-drug conjugates (ADCs).
• Biochemical Research: Employed in studying enzyme-substrate interactions, protein folding, and as a standard in analytical method development for peptide analysis.
• Cosmeceutical Peptides: A potential building block for synthesizing bioactive peptides used in advanced skincare and cosmetic formulations.

Basic Information

Product Name	H-Gly-Nva-Oh
CAS No.	19257-03-5
Molecular Formula	C8H16N2O3
Molecular Weight	188.22 g/mol
Synonyms	Glycyl-L-norvaline; H-Gly-L-Nva-OH; L-Norvalylglycine; Gly-Nva; N-(2-Aminoacetyl)-L-norvaline; 2-[(2-Aminoacetyl)amino]pentanoic acid; (S)-2-(2-Aminoacetamido)pentanoic acid; Peptide building block 19257-03-5
EINECS	Contact for details

Quality Control

Our H-Gly-Nva-Oh is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC for purity, chiral analysis, and identity confirmation, to ensure it meets the stringent requirements of pharmaceutical research. A detailed Certificate of Analysis (COA) is provided with each shipment, guaranteeing traceability, consistency, and compliance with your specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 15-25°C. This material is hygroscopic (moisture-sensitive) and should be handled under dry conditions to maintain stability. For long-term storage, consider desiccants or inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Assay (HPLC)	≥ 98.0%
Optical Rotation	Contact for details
Chiral Purity (HPLC)	≥ 99.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.