Description

n-Acetyl-D-Glutamic Acid is a chiral derivative of glutamic acid, specifically the D-enantiomer acetylated at the amino group. This compound serves as a crucial chiral building block and intermediate in the synthesis of more complex molecules, offering precise stereochemical control. It is primarily utilized by research institutions and manufacturers in the pharmaceutical, agrochemical, and fine chemical industries for applications requiring high enantiomeric purity.

Application

• Pharmaceutical Intermediate: Key chiral synthon for the research and development of active pharmaceutical ingredients (APIs), particularly in neurology and metabolic disorder treatments.
• Biochemical Research: Used as a substrate or inhibitor in enzymatic studies and metabolic pathway analysis.
• Peptide Synthesis: Serves as a protected amino acid derivative in solid-phase and solution-phase peptide chemistry.
• Agrochemical Development: Intermediate in the synthesis of chiral herbicides, fungicides, and plant growth regulators.
• Cosmetic & Personal Care: Potential ingredient in high-end skincare formulations for its moisturizing and skin-conditioning properties.
• Food & Beverage Additive Precursor: Used in the production of flavor enhancers and umami compounds.

Basic Information

Product Name	n-Acetyl-D-Glutamic Acid
CAS No.	19146-55-5
Molecular Formula	C7H11NO5
Molecular Weight	189.17 g/mol
Synonyms	D-2-Acetamidopentanedioic Acid; (R)-2-Acetamidoglutaric Acid; N-Acetyl-D-glutamic Acid; Ac-D-Glu-OH; N-Acetyl-D-glutamate; D-α-Acetamidoglutaric Acid; (2R)-2-Acetamidopentanedioic Acid; NSC 33426
EINECS	242-842-8

Quality Control

Our n-Acetyl-D-Glutamic Acid is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing to ensure identity, purity, and consistency. We provide Certificates of Analysis (COA) with key parameters including assay, enantiomeric excess, and impurity profiles. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring reliable supply for critical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); therefore, the container must be kept tightly sealed after each use to prevent absorption of atmospheric moisture, which can affect quality and stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Enantiomeric Purity (Chiral HPLC)	≥99.0% ee
Loss on Drying	≤1.0%
Residue on Ignition	≤0.1%
Heavy Metals (as Pb)	≤10 ppm
Specific Rotation [α]20/D	+15.0° to +20.0° (c=1 in H2O)

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.