Description

4-Bromo-6-tert-Butylpyrimidine is a versatile brominated pyrimidine derivative, a key building block in advanced organic synthesis. Its value lies in its role as a crucial intermediate for constructing complex molecular architectures, particularly in the development of active pharmaceutical ingredients (APIs) and functional materials. This compound is essential for research chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries who require high-purity intermediates for coupling reactions and heterocyclic chemistry.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of novel drug candidates, especially kinase inhibitors and other small-molecule therapeutics.
• Agrochemical Synthesis: Used in the research and development of new herbicides, fungicides, and pesticides with enhanced efficacy.
• Material Science: Serves as a building block for creating organic electronic materials, such as ligands for OLEDs or molecular sensors.
• Cross-Coupling Reactions: An excellent substrate for Suzuki, Stille, and other palladium-catalyzed cross-coupling reactions to form biaryl systems.
• Chemical Research: A valuable reagent for academic and industrial R&D focused on heterocyclic chemistry and medicinal chemistry.
• Ligand Synthesis: Used in the preparation of specialized ligands for catalysis and coordination chemistry.

Basic Information

Product Name	4-Bromo-6-tert-Butylpyrimidine
CAS No.	19136-36-8
Molecular Formula	C8H11BrN2
Molecular Weight	215.09 g/mol
Synonyms	6-tert-Butyl-4-bromopyrimidine; 4-Bromo-6-(1,1-dimethylethyl)pyrimidine; 4-Bromo-6-(tert-butyl)pyrimidine; Pyrimidine, 4-bromo-6-(1,1-dimethylethyl)-; 4-Bromo-6-tert-butyl-pyrimidine
EINECS	Contact for details

Quality Control

Our 4-Bromo-6-tert-Butylpyrimidine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure high chemical purity and identity confirmation. We provide comprehensive Certificates of Analysis (COA) with every shipment, detailing all relevant specifications. Our quality commitment ensures the material meets the stringent requirements for research and process development applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep the container tightly sealed to prevent moisture absorption and contamination. Handle and store in accordance with good laboratory practices.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.