Description

Methochlorpromazine CAS NO 19077-31-7 is a phenothiazine derivative of significant interest in pharmaceutical research and development. This compound serves as a key intermediate or reference standard in the synthesis and analytical profiling of antipsychotic agents. It is primarily utilized by research institutions and pharmaceutical companies engaged in neuropharmacology and medicinal chemistry. The material is handled under controlled conditions to ensure its integrity for critical applications.

Application

• Pharmaceutical Intermediate: Serves as a crucial building block in the synthesis of advanced phenothiazine-based active pharmaceutical ingredients (APIs).
• Reference Standard: Used in analytical laboratories for method development, validation, and quality control testing of related drug substances and products.
• Biochemical Research: Employed in in vitro studies to investigate dopaminergic and other neurotransmitter receptor interactions and mechanisms of action.
• Metabolite Studies: Acts as a standard for the identification and quantification of drug metabolites in pharmacokinetic and toxicological research.
• Process Development: Utilized in scaling up and optimizing synthetic routes for antipsychotic medications within R&D and pilot plant settings.

Basic Information

Product Name	Methochlorpromazine
CAS No.	19077-31-7
Molecular Formula	C19H23ClN2S
Molecular Weight	346.92 g/mol
Synonyms	Methochlorpromazine; 2-Chloro-10-[3-(4-methyl-1-piperazinyl)propyl]phenothiazine; 2-Chloropromazine; Methochlorpromazine Hydrochloride (salt form); NSC 113929; CPZ analog; Phenothiazine derivative
EINECS	Contact for details

Quality Control

Our Methochlorpromazine is produced and handled under a strict quality management system. Each batch undergoes comprehensive analytical testing, including identification, purity assay, and impurity profiling, to ensure it meets the stringent requirements for research and development use. Certificates of Analysis (COA) detailing specific results for each parameter are available upon request to support your regulatory and quality documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (typically 15-25°C). Keep the container sealed to protect the light-sensitive material from degradation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 1.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.