Description

Fmoc-Asp-Oh CAS NO 19062-05-4 is a high-purity, protected amino acid derivative essential for solid-phase peptide synthesis (SPPS). This compound serves as a critical building block, enabling the precise and efficient construction of complex peptides and proteins in a controlled manner. It is primarily required by research institutions, pharmaceutical developers, and biotechnology companies engaged in drug discovery, proteomics research, and the production of therapeutic peptides.

Application

• Solid-Phase Peptide Synthesis (SPPS): A fundamental Fmoc-protected amino acid for the sequential assembly of peptide chains on resin.
• Pharmaceutical Intermediates: Used in the research and development of peptide-based active pharmaceutical ingredients (APIs) and drug candidates.
• Bioconjugation: Employed to introduce aspartic acid residues with a protected side chain into biomolecules for labeling or functionalization.
• Combinatorial Chemistry: A key component in libraries for high-throughput screening to identify novel bioactive compounds.
• Academic & Industrial Research: Utilized in biochemical studies, protein engineering, and as a standard in analytical method development.
• Custom Peptide Service Providers: A staple raw material for CROs and CDMOs offering bespoke peptide manufacturing services.

Basic Information

Product Name	Fmoc-Asp-Oh
CAS No.	19062-05-4
Molecular Formula	C19H17NO6
Molecular Weight	355.34 g/mol
Synonyms	Fmoc-L-aspartic acid; Fmoc-Asp-OH; Fmoc-Aspartic acid; N-(9-Fluorenylmethoxycarbonyl)-L-aspartic acid; (2S)-2-[(9H-Fluoren-9-ylmethoxy)carbonylamino]butanedioic acid; Fmoc-L-Asp; N-α-Fmoc-L-aspartic acid; Fmoc-Asp(OtBu)-OH (Note: This is the side-chain protected variant; confirm grade)
EINECS	Contact for details

Quality Control

Our Fmoc-Asp-Oh is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and chiral integrity, to ensure it meets the high standards required for sensitive peptide synthesis applications. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and specific impurities is provided with every shipment to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 15-25°C. This product is hygroscopic (moisture-sensitive); keep the container tightly sealed in a desiccated environment to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.5%
Optical Rotation [α]D20	Specification available upon request
Water Content (KF)	≤0.5%
Heavy Metals	≤10 ppm
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.