Description

H-Phe-Nhnh-Z Tfa is a protected amino acid derivative, specifically a hydrazide, widely used as a key building block in peptide synthesis and medicinal chemistry research. Its primary value lies in its role as a versatile intermediate for constructing complex peptide chains and other bioactive molecules with high precision. This compound is essential for researchers and manufacturers in the pharmaceutical, biotechnology, and fine chemical sectors who require high-purity intermediates for drug discovery and development.

Application

• Peptide Synthesis Intermediate: A crucial building block for the solid-phase and solution-phase synthesis of custom peptides and peptidomimetics.
• Pharmaceutical Research: Used in the discovery and development of new therapeutic agents, particularly in oncology and metabolic disease research.
• Bioconjugation: Serves as a linker or spacer molecule for attaching peptides to other biomolecules, surfaces, or drug delivery systems.
• Chemical Biology Probes: Employed in the creation of activity-based probes and other tools for studying enzyme function and protein-protein interactions.
• API Development: Acts as a key intermediate in the synthetic pathway for Active Pharmaceutical Ingredients (APIs) requiring specific chiral centers.
• Academic & Industrial R&D: A standard reagent in laboratories focused on organic synthesis and novel methodology development.

Basic Information

Product Name	H-Phe-Nhnh-Z Tfa
CAS No.	19046-94-7
Molecular Formula	C19H19F3N4O5
Molecular Weight	440.37 g/mol
Synonyms	N-[(Benzyloxy)carbonyl]-L-phenylalanyl hydrazide trifluoroacetate; Z-Phe-NHNH2·TFA; Cbz-Phe-NHNH2·TFA; N-Carbobenzoxy-L-phenylalanyl hydrazide trifluoroacetate; (S)-2-(((Benzyloxy)carbonyl)amino)-3-phenyl-N'-aminopropanehydrazide trifluoroacetate; L-Phenylalanine, N-[(phenylmethoxy)carbonyl]-, hydrazide, 2,2,2-trifluoroacetate (1:1); H-Phe-NHNH-Z TFA salt
EINECS	Contact for details

Quality Control

Our H-Phe-Nhnh-Z Tfa is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical testing, including HPLC for purity, chiral analysis, and identity confirmation. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting compliance with our stringent specifications. We support cGMP manufacturing standards for applications requiring the highest level of quality assurance.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation. For long-term storage, consider desiccants and an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% (L-isomer)
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.