Description

3,5-Diiodo-L-Tyrosine Dihydrate (98%) is a high-purity iodinated derivative of the essential amino acid L-tyrosine, serving as a critical biochemical building block and research reagent. Its primary value lies in its role as a key intermediate for the synthesis of thyroid hormones and other bioactive iodinated compounds, where precise molecular structure and purity are paramount. This product is essential for researchers and manufacturers in the pharmaceutical, biotechnology, and life science sectors, particularly those focused on endocrinology, metabolic research, and the development of diagnostic agents.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of thyroid hormones (e.g., thyroxine, T4) and related analogs.
• Biochemical Research: Used as a substrate or standard in studies of iodine metabolism, tyrosine kinase activity, and enzyme function.
• Diagnostic Agent Development: Serves as a starting material for radiolabeling (e.g., with I-125 or I-131) to create tracers for medical imaging and diagnostic tests.
• Reference Standard: Employed as a high-purity analytical standard in HPLC, LC-MS, and other quality control methods for related compounds.
• Peptide Synthesis: Incorporated into custom peptides to study the effects of iodination on protein structure and function.
• Nutritional Science Research: Investigated for its role in iodine utilization and thyroid function in experimental models.

Basic Information

Item	Details
Product Name	3,5-Diiodo-L-Tyrosine Dihydrate (98%)
CAS No.	18835-59-1
Molecular Formula	C9H9I2NO4 · 2H2O
Molecular Weight	505.00 g/mol (for dihydrate)
Synonyms	3,5-Diiodotyrosine Dihydrate; L-3,5-Diiodotyrosine Dihydrate; (2S)-2-Amino-3-(4-hydroxy-3,5-diiodophenyl)propanoic acid dihydrate; DIT; 3,5-DIIODO-L-TYROSINE; 3,5-Diiodo-4-hydroxyphenylalanine dihydrate; 18835-59-1; Diiodotyrosine
EINECS	242-628-9

Quality Control

Our 3,5-Diiodo-L-Tyrosine Dihydrate is produced and tested under a rigorous quality management system. Each batch is analyzed to confirm identity, purity, and conformance to specifications using advanced techniques including HPLC, IR spectroscopy, and elemental analysis. A comprehensive Certificate of Analysis (COA) detailing all test results is provided with every shipment to ensure full traceability and compliance with your research or production requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its light-sensitive and easily oxidized nature, it is recommended to handle under an inert atmosphere for long-term storage and to minimize headspace in opened containers to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	6.0 - 8.0% (Theoretical for dihydrate: ~7.14%)
Specific Rotation	Contact for details
Heavy Metals	< 20 ppm
Residue on Ignition	< 0.1%
Related Substances (HPLC)	Individual impurity ≤ 0.5%; Total impurities ≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.