Description

1H-Pyrimido[4,5-B][1,4]Benzodiazepine-2,4,6(3H)-Trione, 5,11-Dihydro-1,3-Dimethyl- is a high-purity heterocyclic organic compound belonging to the benzodiazepine class, serving as a critical advanced pharmaceutical intermediate. Its complex fused-ring structure makes it a valuable building block for the synthesis of novel active pharmaceutical ingredients (APIs) and fine chemicals. This product is essential for research and development laboratories, pharmaceutical manufacturers, and fine chemical producers focused on creating new therapeutic agents and specialized organic molecules.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel benzodiazepine-derived active pharmaceutical ingredients (APIs) for central nervous system (CNS) research.
• Medicinal Chemistry Research: Used as a core scaffold in drug discovery programs for developing new therapeutic compounds with potential anxiolytic, sedative, or other pharmacological activities.
• Fine Chemical Synthesis: Serves as a sophisticated building block for constructing complex heterocyclic compounds in advanced organic synthesis.
• Biochemical Research: Employed in studies investigating molecular interactions and receptor binding mechanisms due to its specific structural features.
• Reference Standard: Utilized as a high-purity analytical standard for quality control and method development in pharmaceutical analysis.

Basic Information

Product Name	1H-Pyrimido[4,5-B][1,4]Benzodiazepine-2,4,6(3H)-Trione, 5,11-Dihydro-1,3-Dimethyl-
CAS No.	18830-60-9
Molecular Formula	C₁₃H₁₂N₄O₃
Molecular Weight	272.26 g/mol
Synonyms	5,11-Dihydro-1,3-dimethyl-1H-pyrimido[4,5-b][1,4]benzodiazepine-2,4,6(3H)-trione; 1,3-Dimethyl-5,11-dihydro-1H-pyrimido[4,5-b][1,4]benzodiazepine-2,4,6(3H)-trione; 1,3-Dimethyl-5,11-dihydro-1H-pyrimido[4,5-b][1,4]benzodiazepine-2,4,6-trione; 1,3-Dimethyl-5,11-dihydro-1H-pyrimido[4,5-b][1,4]benzodiazepine-2,4,6(3H,5H,11H)-trione; 1,3-Dimethyl-5,11-dihydro-1H-pyrimido[4,5-b][1,4]benzodiazepine-2,4,6(3H)-trione; 1,3-Dimethyl-5,11-dihydro-1H-pyrimido[4,5-b][1,4]benzodiazepine-2,4,6(3H,5H,11H)-trione; 1,3-Dimethyl-5,11-dihydro-1H-pyrimido[4,5-b][1,4]benzodiazepine-2,4,6(3H)-trione; 1,3-Dimethyl-5,11-dihydro-1H-pyrimido[4,5-b][1,4]benzodiazepine-2,4,6(3H,5H,11H)-trione
EINECS	Contact for details

Quality Control

Our 1H-Pyrimido[4,5-B][1,4]Benzodiazepine-2,4,6(3H)-Trione, 5,11-Dihydro-1,3-Dimethyl- is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. All products undergo rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to meet the stringent requirements for pharmaceutical intermediates. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment to support your quality assurance and regulatory compliance.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from incompatible materials. For long-term storage, consider storing under an inert atmosphere to maintain product stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.