Description

Z-Leu-Met-Oh is a protected dipeptide derivative, specifically the benzyloxycarbonyl (Z) protected form of the Leu-Met sequence. This compound is a crucial building block in solid-phase peptide synthesis (SPPS), offering precise control over peptide chain assembly. It is primarily utilized by research institutions and pharmaceutical companies engaged in the development of novel peptides, peptidomimetics, and biochemical probes. The product ensures high purity and reliable performance for demanding synthetic applications.

Application

• Solid-Phase Peptide Synthesis (SPPS): A fundamental building block for the controlled, sequential assembly of custom peptide sequences in research and development.
• Pharmaceutical Intermediates: Serves as a key intermediate in the synthesis of potential therapeutic peptides targeting various biological pathways.
• Biochemical Research: Used in studies of enzyme-substrate interactions, protein folding, and the structure-activity relationships (SAR) of peptides.
• Peptidomimetic Development: Acts as a starting material for creating modified peptide analogs with enhanced stability or biological activity.
• Custom Peptide Services: Employed by CROs and CDMOs to manufacture bespoke peptides for client projects.
• Academic Research: A standard reagent in university laboratories for training and investigations in organic chemistry and biochemistry.

Basic Information

Product Name	Z-Leu-Met-Oh
CAS No.	18830-16-5
Molecular Formula	C20H30N2O5S
Molecular Weight	410.53 g/mol
Synonyms	N-Cbz-Leu-Met-OH; N-Carbobenzoxy-L-leucyl-L-methionine; Z-L-Leucyl-L-methionine; Cbz-Leu-Met-OH; Benzyloxycarbonyl-L-leucyl-L-methionine; Nα-Carbobenzyloxy-L-leucyl-L-methionine; (2S)-2-[[(2S)-2-[[(Benzyloxy)carbonyl]amino]-4-methylpentanoyl]amino]-4-(methylsulfanyl)butanoic acid; Z-Leu-Met
EINECS	Contact for details

Quality Control

Our Z-Leu-Met-Oh is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, chiral analysis for enantiomeric integrity, and identity confirmation via spectroscopic methods. We provide a Certificate of Analysis (COA) with every shipment, detailing all relevant specifications to ensure the material meets your research and development requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation. For long-term storage, consider desiccated conditions.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC/MS)	Conforms
Purity (HPLC)	≥ 98.0%
Optical Rotation	Contact for details
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.