Description

Boc-Ala-D-Glu(Obzl)-Nh2 is a protected dipeptide building block used in solid-phase peptide synthesis (SPPS). This compound matters for its role in constructing complex peptide sequences with precise stereochemistry, where the Boc (tert-butoxycarbonyl) group provides orthogonal protection. Pharmaceutical researchers and fine chemical manufacturers need it for the development of therapeutic peptides, peptidomimetics, and biochemical research tools.

Application

• Pharmaceutical Intermediates: Key building block for the synthesis of novel therapeutic peptides targeting metabolic and neurological disorders.
• Peptidomimetic Research: Used to create stable, bioavailable analogs of natural peptides in drug discovery programs.
• Bioconjugation: Serves as a precursor for creating peptide-based linkers or tags for antibody-drug conjugates (ADCs) and diagnostic probes.
• Biochemical Tool Development: Essential for producing custom peptide substrates, inhibitors, or standards for enzymatic assays and proteomics research.
• Academic & Contract Research: Employed in university and CRO laboratories for fundamental peptide chemistry studies and custom synthesis projects.

Basic Information

Item	Detail
Product Name	Boc-Ala-D-Glu(Obzl)-Nh2
CAS No.	18814-49-8
Molecular Formula	C20H29N3O6
Molecular Weight	407.46 g/mol
Synonyms	Boc-Ala-D-Glu(OBzl)-NH2; N-(tert-Butoxycarbonyl)-L-alanyl-D-glutamic acid α-benzyl ester amide; Boc-L-Ala-D-Glu(OBzl)-NH2; Boc-Ala-ψ[CH2NH]-Glu(OBzl); (2R)-2-[[(2S)-2-[(2-methylpropan-2-yl)oxycarbonylamino]propanoyl]amino]-5-(benzyloxy)-5-oxopentanamide; tert-Butyl (S)-1-((R)-1-amino-5-(benzyloxy)-1,5-dioxopentan-2-ylamino)-1-oxopropan-2-ylcarbamate; Peptide Synthesis Building Block Boc-Ala-D-Glu(OBzl)-NH2.
EINECS	Contact for details

Quality Control

Our Boc-Ala-D-Glu(Obzl)-Nh2 is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity, chiral analysis for stereochemical integrity, and NMR for structural confirmation, to ensure compliance with research and pharmaceutical intermediate standards. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 15-25°C. This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent decomposition. For long-term storage, consider desiccation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% (D-configuration at Glu)
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.