Description

6-Azauracil is a heterocyclic organic compound and a structural analog of uracil, where a nitrogen atom replaces the carbon at the 6-position. This modification makes it a valuable biochemical tool and a key intermediate in the synthesis of nucleoside analogs and other bioactive molecules. It is primarily utilized by research institutions and pharmaceutical companies engaged in antiviral, anticancer, and metabolic pathway research. Our supply of 6-Azauracil CAS NO 18802-37-4 ensures high purity and batch-to-batch consistency for critical applications.

Application

• Biochemical Research: Used as a specific inhibitor of orotidine-5'-phosphate decarboxylase (ODCase) to study de novo pyrimidine biosynthesis pathways.
• Pharmaceutical Intermediates: Serves as a crucial building block in the synthesis of novel nucleoside analogs with potential antiviral and antitumor activities.
• Antifungal Agent Development: Investigated for its role in creating compounds that target fungal pyrimidine metabolism.
• Plant Growth Regulation: Studied for its effects on plant metabolism and potential use as a plant growth regulator.
• Reference Standard: Employed as an analytical standard in quality control laboratories for method development and validation.
• Enzyme Studies: Utilized in enzymatic assays to probe the mechanism and inhibition of enzymes involved in nucleotide metabolism.

Basic Information

Product Name	6-Azauracil
CAS No.	18802-37-4
Molecular Formula	C3H3N3O2
Molecular Weight	113.07 g/mol
Synonyms	1,2,4-Triazine-3,5(2H,4H)-dione; 2,4-Dihydroxy-1,2,4-triazine; 6-Azauracil; Azauracil; 1,2,4-Triazine-3,5-diol; 3,5-Dihydroxy-1,2,4-triazine; NSC 742; U-11634
EINECS	242-581-8

Quality Control

Every batch of our 6-Azauracil is produced and tested under strict quality management protocols to ensure it meets the high standards required for research and synthesis. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing purity, identity, and impurity profiles. Our quality systems are designed to support applications requiring reliable and reproducible performance, from basic research to advanced pharmaceutical development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). The product is hygroscopic (moisture-sensitive) and should be handled under dry conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Loss on Drying	≤1.0%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm
Related Substances (HPLC)	Total impurities ≤2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.