Description

H-Pro-Gln-Oh CAS NO 18668-08-1 is a high-purity dipeptide derivative, specifically L-Prolyl-L-glutamine. This compound serves as a critical building block and intermediate in advanced organic synthesis and pharmaceutical research. It is essential for researchers and manufacturers in the pharmaceutical, biotechnology, and fine chemical sectors who require high-quality, well-characterized peptide intermediates for drug discovery, development, and production.

Application

• Pharmaceutical Intermediate: A key synthon in the synthesis of complex peptide-based active pharmaceutical ingredients (APIs) and prodrugs.
• Biochemical Research: Used as a substrate or standard in enzymatic studies, metabolic pathway analysis, and proteomics research.
• Peptide Synthesis: Serves as a protected dipeptide unit in solid-phase and solution-phase peptide synthesis for constructing longer peptide chains.
• Nutraceutical Development: Investigated for potential applications in specialized dietary supplements and functional food ingredients.
• Cosmetic Peptides: A potential raw material for the development of advanced anti-aging and skin-care peptide formulations.
• Reference Standard: Employed as a high-purity analytical standard for quality control and method development in analytical laboratories.

Basic Information

Product Name	H-Pro-Gln-Oh
CAS No.	18668-08-1
Molecular Formula	C11H19N3O4
Molecular Weight	257.29 g/mol
Synonyms	L-Prolyl-L-glutamine; Pro-Gln; H-Pro-Gln-OH; L-Pro-L-Gln; N-(L-Prolyl)-L-glutamine; (S)-2-((S)-Pyrrolidine-2-carboxamido)pentanediamic acid; Proline glutamine dipeptide; PGQ
EINECS	Contact for details

Quality Control

Our H-Pro-Gln-Oh is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, chiral analysis, and identity confirmation (IR, NMR) to ensure it meets the stringent requirements for research and production. Certificates of Analysis (COA) with detailed chromatograms and spectral data are provided to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C (refrigerated) or as specified on the label or COA. This product is hygroscopic (moisture-sensitive). Allow the container to reach room temperature before opening to prevent condensation and moisture ingress.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Optical Rotation	[α]²⁰D: Specific range available on COA
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Single Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.