Description

D-Leucyl-Glycyl-Glycine is a synthetic tripeptide derivative featuring a D-configuration leucine residue. This specific stereochemistry makes it a valuable building block in pharmaceutical research and peptide synthesis, offering unique metabolic stability and resistance to enzymatic degradation. It is primarily utilized by researchers and manufacturers in the life sciences sector for developing novel therapeutic agents, diagnostic tools, and biochemical probes.

Application

• Pharmaceutical Intermediate: Serves as a key chiral precursor in the synthesis of more complex peptide-based drugs and active pharmaceutical ingredients (APIs).
• Biochemical Research: Used as a standard or substrate in enzymatic studies, particularly those investigating peptidase specificity and activity.
• Peptide Library Construction: An essential component in combinatorial chemistry for creating diverse peptide libraries to screen for biological activity.
• Proteomics & Diagnostics: Employed in the development of specialized reagents, affinity tags, and calibration standards for mass spectrometry and diagnostic assays.
• Cosmeceutical Development: Investigated for potential use in advanced skincare formulations targeting specific biological pathways.

Basic Information

Product Name	D-Leucyl-Glycyl-Glycine
CAS No.	18625-22-4
Molecular Formula	C10H19N3O4
Molecular Weight	245.28 g/mol
Synonyms	D-Leu-Gly-Gly; H-D-Leu-Gly-Gly-OH; (R)-2-((2-Aminoacetamido)methyl)-4-methylpentanoic acid; D-Leucylglycylglycine; Glycylglycine, N-[(1R)-1-[(1-amino-2-oxoethyl)carbamoyl]-3-methylbutyl]-; D-LGG; N-[(R)-2-Amino-4-methyl-1-oxopentyl]glycylglycine
EINECS	Contact for details

Quality Control

Our D-Leucyl-Glycyl-Glycine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, chiral purity analysis, and identity confirmation by spectroscopic methods, to ensure it meets stringent specifications for research and development use. Certificates of Analysis (COA) detailing all test results are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept in a desiccated environment to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% D-isomer
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.