Description

3-Sulfamoyl-L-Alanine is a specialized amino acid derivative featuring a sulfamoyl functional group. This compound is a key chiral building block and intermediate in the synthesis of more complex molecules, particularly in pharmaceutical research and development. It is primarily utilized by research institutions and manufacturers in the life sciences sector for applications in medicinal chemistry and as a precursor for bioactive compounds.

Application

• Pharmaceutical Intermediate: Serves as a critical chiral synthon in the research and development of new active pharmaceutical ingredients (APIs), especially for sulfonamide-based drugs.
• Medicinal Chemistry Research: Used as a building block for constructing novel molecular libraries and exploring structure-activity relationships (SAR) in drug discovery programs.
• Biochemical Research: Acts as a substrate or inhibitor analog in enzymatic studies, particularly those involving enzymes that interact with sulfonamide or amino acid motifs.
• Peptide Modification: Incorporated into synthetic peptides to introduce the sulfamoyl group, altering peptide properties for research into new therapeutic modalities.
• Reference Standard: Employed as a high-purity analytical standard for quality control and method development in analytical laboratories.

Basic Information

Product Name	3-Sulfamoyl-L-Alanine
CAS No.	18625-03-1
Molecular Formula	C₃H₈N₂O₄S
Molecular Weight	168.17 g/mol
Synonyms	L-2-Amino-3-sulfamoylpropanoic acid; (S)-2-Amino-3-sulfamoylpropanoic acid; 3-Sulfamoyl-L-alanine; 3-Sulfamoylalanine; Alanine, 3-sulfamoyl-; NSC 113935
EINECS	Contact for details

Quality Control

Our 3-Sulfamoyl-L-Alanine is manufactured under a strict quality management system. Each batch undergoes comprehensive analytical testing, including identity confirmation by IR and NMR, purity assessment by HPLC, and specific tests for related substances and residual solvents. We provide full traceability and Certificates of Analysis (COA) are available for all shipments, ensuring compliance with your research and development specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to prevent moisture absorption, which can affect stability and handling properties.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Optical Rotation	[α]²⁰D: Specific range available on COA
Loss on Drying	≤ 1.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Heavy Metals	≤ 20 ppm
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.