Description

Cyclo-L-Trp-L-His CAS NO 18610-65-6 is a high-purity cyclic dipeptide composed of L-Tryptophan and L-Histidine. This compound is valued for its structural role as a building block in advanced peptide synthesis and its potential as a key intermediate in pharmaceutical research. It is primarily utilized by research institutions and manufacturers in the pharmaceutical, biotechnology, and nutraceutical sectors for developing novel therapeutic agents and bioactive compounds.

Application

• Pharmaceutical Intermediate: Serves as a critical building block for the synthesis of more complex peptides and peptidomimetics with potential therapeutic activity.
• Biochemical Research: Used as a standard or reagent in studies investigating enzyme-substrate interactions, receptor binding, and signal transduction pathways.
• Nutraceutical Development: Explored as a precursor for bioactive compounds in dietary supplements and functional food ingredients.
• Cosmetic Peptides: Investigated for potential applications in anti-aging and skin-care formulations due to its amino acid constituents.
• Chemical Biology Probes: Utilized in the design and synthesis of probes for studying biological processes and protein functions.

Basic Information

Product Name	Cyclo-L-Trp-L-His
CAS No.	18610-65-6
Molecular Formula	C17H17N5O2
Molecular Weight	323.35 g/mol
Synonyms	Cyclo(L-Tryptophyl-L-Histidyl); L-Histidyl-L-tryptophan anhydride; Cyclo(His-Trp); Cyclo(histidyltryptophan); 3-(1H-Imidazol-4-ylmethyl)-6-(1H-indol-3-ylmethyl)-2,5-piperazinedione; DKPs (Diketopiperazines) derivative; Cyclo(Trp-His); Cyclotryptophylhistidine
EINECS	Contact for details

Quality Control

Our Cyclo-L-Trp-L-His is manufactured under a strict quality management system. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for research and development. Certificates of Analysis (COA) documenting all critical parameters are available upon request to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.