Description

9-(Trimethylsilyl)-2,6-Bis(trimethylsiloxy)-9H-Purine is a silylated purine derivative, a key building block in advanced organic synthesis and pharmaceutical research. This compound is valued for its role as a protected nucleobase intermediate, enabling precise chemical modifications that are difficult to achieve with unprotected purines. It is primarily utilized by researchers and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries for developing novel active ingredients and high-value fine chemicals.

Application

• Pharmaceutical Intermediate: A crucial precursor in the synthesis of novel nucleoside analogs, antiviral agents, and other purine-based active pharmaceutical ingredients (APIs).
• Agrochemical Research: Used in the development of new herbicides, fungicides, and plant growth regulators that incorporate modified purine structures.
• Organosilicon Chemistry: Serves as a model compound or starting material for studying silyl group transfer reactions and protecting group strategies in complex molecule assembly.
• Bioconjugation & Probe Synthesis: Employed in creating labeled nucleotides or purine derivatives for diagnostic assays, imaging probes, and biochemical research tools.
• Material Science: Potential use as a monomer or functional additive in the synthesis of specialty polymers and advanced organic materials.

Basic Information

Product Name	9-(Trimethylsilyl)-2,6-Bis(trimethylsiloxy)-9H-Purine
CAS No.	18551-03-6
Molecular Formula	C14H28N4O2Si3
Molecular Weight	384.66 g/mol
Synonyms	9H-Purine, 9-(trimethylsilyl)-2,6-bis[(trimethylsilyl)oxy]-; 2,6-Bis(trimethylsiloxy)-9-(trimethylsilyl)purine; 9-(Trimethylsilyl)purine-2,6-bis(trimethylsilyl ether); TMS-Purine derivative; Silylated Hypoxanthine derivative; N9-Trimethylsilyl-2,6-bis-O-trimethylsilylpurine
EINECS	Contact for details

Quality Control

Our 9-(Trimethylsilyl)-2,6-Bis(trimethylsiloxy)-9H-Purine is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and GC, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with every shipment, documenting all critical quality parameters. Our quality systems are designed to support cGMP and ISO standards for research and development applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive); therefore, containers must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider using desiccants or an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.