Description

Ethyl 3-(4-Fluoroanilino)Crotonate is a specialized organic compound featuring a fluorinated aniline moiety linked to a crotonate ester. This structure makes it a valuable key intermediate in the synthesis of more complex molecules, particularly in advanced pharmaceutical and agrochemical research. It is primarily sought after by R&D chemists and process development scientists working on novel active ingredients, where its unique scaffold enables the introduction of specific functional groups.

Application

• Pharmaceutical Intermediate: A crucial building block in the synthesis of potential drug candidates, especially those targeting central nervous system (CNS) disorders or possessing anti-inflammatory properties.
• Agrochemical Synthesis: Serves as a precursor in the development of new herbicides, fungicides, or insecticides, leveraging the bioactivity of the fluoroaniline group.
• Organic Synthesis & Research: Used in academic and industrial laboratories for constructing complex heterocycles or as a model compound in methodological studies involving enamine chemistry.
• Material Science Precursor: Potential use in the synthesis of specialty monomers or ligands for catalysts used in polymer science.

Basic Information

Item	Detail
Product Name	Ethyl 3-(4-Fluoroanilino)Crotonate
CAS No.	18529-17-4
Molecular Formula	C12H14FNO2
Molecular Weight	223.24 g/mol
Synonyms	Ethyl (E)-3-[(4-fluorophenyl)amino]but-2-enoate; Ethyl 3-[(4-fluorophenyl)amino]-2-butenoate; 2-Butenoic acid, 3-[(4-fluorophenyl)amino]-, ethyl ester; 3-(4-Fluoroanilino)crotonic acid ethyl ester; Ethyl β-[(4-fluorophenyl)amino]crotonate; 18529-17-4; Ethyl 3-(p-fluoroanilino)crotonate
EINECS	Contact for details

Quality Control

Our Ethyl 3-(4-Fluoroanilino)Crotonate is manufactured under a strict quality management system. Every batch undergoes comprehensive analytical testing, including HPLC for purity and spectroscopic identification (IR, NMR), to ensure it meets precise customer specifications. A Certificate of Analysis (COA) detailing all test results is provided with each shipment to guarantee traceability and consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (typically 15-25°C). Keep away from strong oxidizing agents and bases.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.