Description

2-(2,3-Difluorophenyl)Propan-2-Amine is a specialized fluorinated amine building block of significant interest in advanced organic synthesis. This compound matters for its role as a key intermediate in the development of active pharmaceutical ingredients (APIs) and agrochemicals, where the difluorophenyl moiety can impart desirable metabolic stability and bioavailability. It is primarily needed by research and development chemists, process development scientists, and manufacturers in the pharmaceutical, agrochemical, and material science industries seeking to incorporate this unique fluorinated scaffold into novel molecules.

Application

• Pharmaceutical Intermediate: A critical building block for the synthesis of novel drug candidates, particularly in central nervous system (CNS) and anti-inflammatory therapeutic areas.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and insecticides, where fluorine atoms enhance biological activity.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands used in asymmetric catalysis and metal-organic frameworks (MOFs).
• Material Science Research: Employed in the development of fluorinated polymers and advanced organic electronic materials.
• Chemical Biology Probes: Utilized as a scaffold for designing molecular probes and inhibitors to study enzyme function and biological pathways.
• Custom Synthesis and Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for bespoke synthesis projects requiring fluorinated aromatic amines.

Basic Information

Product Name	2-(2,3-Difluorophenyl)Propan-2-Amine
CAS No.	18355-84-5
Molecular Formula	C9H11F2N
Molecular Weight	171.19 g/mol
Synonyms	2-(2,3-Difluorophenyl)-2-propanamine; 1-(2,3-Difluorophenyl)-1-methylethylamine; α,α-Dimethyl-2,3-difluorobenzylamine; 2-Amino-2-(2,3-difluorophenyl)propane; 2,3-Difluoro-α,α-dimethylbenzylamine; 2-(2,3-Difluorophenyl)isopropylamine; 2,3-DFPA
EINECS	Contact for details

Quality Control

Our 2-(2,3-Difluorophenyl)Propan-2-Amine is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure high chemical purity and identity confirmation. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all relevant specifications. Our quality commitment aligns with cGMP principles where applicable, supporting our customers' needs in regulated industries.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Keep away from heat, sparks, and open flame. Due to its amine functionality and light-sensitive nature, long-term storage under an inert atmosphere (e.g., nitrogen or argon) is recommended for optimal stability.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid or solid
Identification (IR)	Conforms to structure
Purity (HPLC/GC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.