Description

2-Bromo-6-Fluoro-4-Methylaniline is a halogenated aniline derivative that serves as a versatile and critical building block in advanced organic synthesis. Its unique substitution pattern makes it a valuable intermediate for constructing complex molecules with tailored properties. This compound is primarily utilized by research institutions and industrial manufacturers in the pharmaceutical and agrochemical sectors for the development of new active ingredients.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly in the development of active pharmaceutical ingredients (APIs) with bromine and fluorine substituents for enhanced bioactivity and metabolic stability.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides, herbicides, and fungicides, where the fluorine atom can improve lipophilicity and membrane permeability.
• Material Science Research: Employed as a monomer or functionalization agent in the development of specialty polymers, liquid crystals, and organic electronic materials.
• Dye and Pigment Manufacturing: Acts as an intermediate for synthesizing complex azo dyes and high-performance pigments, leveraging the aniline core for color development.
• Cross-Coupling Reactions: Serves as a substrate in palladium-catalyzed reactions (e.g., Buchwald-Hartwig amination, Suzuki coupling) to create biaryl structures common in many functional molecules.

Basic Information

Item	Details
Product Name	2-Bromo-6-Fluoro-4-Methylaniline
CAS No.	18349-09-2
Molecular Formula	C7H7BrFN
Molecular Weight	204.04 g/mol
Synonyms	4-Amino-3-bromo-5-fluorotoluene; 3-Bromo-5-fluoro-4-methylaniline; 2-Bromo-6-fluoro-p-toluidine; 2-Bromo-6-fluoro-4-methylbenzenamine; 4-Methyl-2-bromo-6-fluoroaniline; Benzenamine, 2-bromo-6-fluoro-4-methyl-; 18349-09-2
EINECS	Contact for details

Quality Control

Our 2-Bromo-6-Fluoro-4-Methylaniline is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing to ensure identity, purity, and consistency. We provide Certificates of Analysis (COA) with detailed results from techniques including HPLC, GC, NMR, and IR spectroscopy. Our quality commitment ensures the material meets the stringent requirements for research and scale-up applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from heat, open flames, and incompatible materials. Due to its light-sensitive nature, handling and packaging should minimize exposure to direct light.

Specification

Item	Specification
Appearance	Off-white to light brown crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.